Evidence map›Paper›PMID 30893369›Full record

ArticlePloS one2019

Development of a risk prediction model for infection-related mortality in patients undergoing peritoneal dialysis.

Hiroaki Tsujikawa, Shigeru Tanaka, Yuta Matsukuma, Hidetoshi Kanai, Kumiko Torisu, Toshiaki Nakano, Kazuhiko Tsuruya, Takanari Kitazono

Abstract readMulticenter Study
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hiroaki TsujikawaDepartment of Medicine and Clinical Science, Kyushu University, Fukuoka, Japan.
Shigeru TanakaFukuoka Dental College, Fukuoka, Japan.
Yuta MatsukumaDepartment of Medicine and Clinical Science, Kyushu University, Fukuoka, Japan.
Hidetoshi KanaiKokura Memorial Hospital, Fukuoka, Japan.
Kumiko TorisuDepartment of Integrated Therapy for Chronic Kidney Disease, Kyushu University, Fukuoka, Japan.
Toshiaki NakanoDepartment of Medicine and Clinical Science, Kyushu University, Fukuoka, Japan.ORCID 0000-0001-9235-5615
Kazuhiko TsuruyaDepartment of Integrated Therapy for Chronic Kidney Disease, Kyushu University, Fukuoka, Japan.
Takanari KitazonoDepartment of Medicine and Clinical Science, Kyushu University, Fukuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssessment of infection-related mortality remains inadequate in patients undergoing peritoneal dialysis. This study was performed to develop a risk model for predicting the 2-year infection-related mortality risk in patients undergoing peritoneal dialysis.

methodsThe study cohort comprised 606 patients who started and continued peritoneal dialysis for 90 at least days and was drawn from the Fukuoka Peritoneal Dialysis Database Registry Study in Japan. The patients were registered from 1 January 2006 to 31 December 2016 and followed up until 31 December 2017. To generate a prediction rule, the score for each variable was weighted by the regression coefficients calculated using a Cox proportional hazard model adjusted by risk factors for infection-related mortality, including patient characteristics, comorbidities, and laboratory data.

resultsDuring the follow-up period (median, 2.2 years), 138 patients died; 58 of them of infectious disease. The final model for infection-related mortality comprises six factors: age, sex, serum albumin, serum creatinine, total cholesterol, and weekly renal Kt/V. The incidence of infection-related mortality increased linearly with increasing total risk score (P for trend <0.001). Furthermore, the prediction model showed adequate discrimination (c-statistic = 0.79 [0.72-0.86]) and calibration (Hosmer-Lemeshow test, P = 0.47).

conclusionIn this study, we developed a new model using clinical measures for predicting infection-related mortality in patients undergoing peritoneal dialysis.

Indexed as

AgedCohort StudiesCreatinineFemaleHumansIncidenceJapanMaleMiddle AgedPeritoneal DialysisProportional Hazards ModelsRegistriesRetrospective StudiesRisk FactorsCreatinine

Identifiers

PMID30893369
PMCPMC6426225

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.