SynthesisPloS one2019
Metabolic costs of activities of daily living in persons with a lower limb amputation: A systematic review and meta-analysis.
Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Surgical Site Infections in Major Lower Limb Amputation (SIMBA): international multicentre study.BJS open · 2026Observational
- Physical activity levels are low in the days, weeks, and months following dysvascular major lower limb amputation.Journal of rehabilitation medicine · 2026Observational
- Optimizing below knee amputation osteotomy length: a ratio-based approach.OTA international : the open access journal of orthopaedic trauma · 2025Article
- Wearing Time, Quality of Life, and Complications of Lower Limb Bone-anchored Prostheses: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2025Article
- A behaviour change intervention promoting physical activity following dysvascular amputation: Protocol for a pilot study.PloS one · 2025Article
- Relative Aerobic Load of Daily Activities in Individuals with Lower Limb Amputation: A pilot study.Canadian prosthetics & orthotics journal · 2025Article
- Appraising the Physical Activity Levels of Saudis with Physical Disabilities: Effects of Disability Type, Mobility Assistive Devices, and Demographic Factors.Healthcare (Basel, Switzerland) · 2024Article
- A Deep Learning Framework for End-to-End Control of Powered Prostheses.IEEE robotics and automation letters · 2024Article
- Hemodynamic and Metabolic Responses to Moderate and Vigorous Cycle Ergometry in Men Who Have Had Transtibial Amputation.International journal of environmental research and public health · 2024Article
- Periodic health evaluation in Para athletes: a position statement based on expert consensus.BMJ open sport & exercise medicine · 2024Article
- Assessment of isokinetic hip muscle strength and predictors in patients with lower limb amputation: A cross-sectional study.Turkish journal of physical medicine and rehabilitation · 2023Article
- Improving Amputee Endurance over Activities of Daily Living with a Robotic Knee-Ankle Prosthesis: A Case Study.Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and Systems · 2023Article
- Measurement properties of device-based physical activity instruments in ambulatory adults with physical disabilities and/or chronic diseases: a scoping review.BMC sports science, medicine & rehabilitation · 2023Article
- Match Running Performance Profile and Heart Rate Response in Amputee Soccer Players.International journal of environmental research and public health · 2023Article
- Effectiveness of (Active) Lifestyle Interventions in People With a Lower Limb Amputation: A Systematic Review.Archives of rehabilitation research and clinical translation · 2022Review
- The psychological impact of instrumental activities of daily living on people with simulated age-related macular degeneration.BJPsych open · 2022Article
- Knee extensor power predicts six-minute walk test performance in people with transfemoral amputations.PM & R : the journal of injury, function, and rehabilitation · 2022Article
- A Computational Gait Model With a Below-Knee Amputation and a Semi-Active Variable-Stiffness Foot Prosthesis.Journal of biomechanical engineering · 2021Article
- Outcomes of Total Knee Arthroplasty with a Prior Contralateral Above-Knee Amputation: A Report of 10 Cases.Arthroplasty today · 2020Article
- Limb Salvage for Musculoskeletal Tumors in the Austere Environment: Review of the Literature With Illustrative Cases Regarding Considerations and Pitfalls.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo systematically review the literature on the metabolic costs of activities of daily living (ADL) in persons with a lower limb amputation (LLA). DATA SOURCES: A literature search was undertaken in the Pubmed, Embase, CINAHL, CENTRAL, and PsycINFO databases using keywords and synonyms for LLA, metabolic costs, and ADL. The last search was performed on November 29th, 2017. STUDY SELECTION: Studies were included if they met the following 2 criteria: participants were adults with a (unilateral or bilateral) LLA and metabolic costs were measured while participants performed a physical activity or ADL. DATA EXTRACTION AND SYNTHESIS: Data of 1,912 participants from 61 studies were included in the systematic review and meta-analysis. The studies used different terms to describe metabolic costs. Participants were recruited in different settings, relatively healthy, with few comorbidities. Limited data were available on metabolic costs of other activities than walking with a prosthesis. A linear mixed model analysis was performed based on the means reported, with study as unit of analysis and test results of different groups and measurement conditions as repeated measures within the unit of analysis. Predictors entered in the analysis were e.g. level and reason of amputation, age, weight, and height. During walking, oxygen consumption (ml O2/kg/min) and heart rate (beats/min) increased with a higher walking speed and a more proximal amputation. Additionally, oxygen consumption was determined by the interaction terms walking speed x amputation level and walking speed squared. Heart rate was determined by the interaction term walking speed squared.
conclusionDuring walking, oxygen consumption (ml O2/kg/min) and heart rate (beats/min) increased with a higher walking speed and a more proximal amputation. Data on metabolic costs of other activities were limited. The poor quality of the studies and the relatively healthy participants limited generalizability of the results of the meta-analysis.
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