ArticleJournal of the Chinese Medical Association : JCMA2019
Change of the levels of trace elements and heavy metals in threatened abortion.
Article in Journal of the Chinese Medical Association : JCMA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Impact of lipid-based nutritional supplementation on cardio metabolic risk factors in underweight pre-eclamptic primigravidas: A randomized controlled trial.BMC pregnancy and childbirth · 2026Trial
- Effect of Lipid-Based Multiple Micronutrients Supplementation in Underweight Primigravida Pre-Eclamptic Women on Maternal and Pregnancy Outcomes: Randomized Clinical Trial.Medicina (Kaunas, Lithuania) · 2022Trial
- Maternal consumption of urbanized diet compromises early-life health in association with gut microbiota.Gut microbes · 2025Review
- Copper homeostasis and pregnancy complications: a comprehensive review.Journal of assisted reproduction and genetics · 2025Review
- The Relationship Between Heavy Metals and Missed Abortion: Using Mediation of Serum Hormones.Biological trace element research · 2024Article
- Comparison of zinc levels in mothers with and without abortion: A systematic review and meta-analysiss.Heliyon · 2024Article
- Trace element concentrations in blood samples from dairy cows with uterine torsion and their neonatal calves.Veterinary world · 2023Article
- Micronutrients in Food Supplements for Pregnant Women: European Health Claims Assessment.Nutrients · 2023Article
- Maternal Serum Zinc, Copper, Magnesium, and Iron in Spontaneous Abortions.Indian journal of clinical biochemistry : IJCB · 2023Article
- Heavy metals and metalloids exposure andFrontiers in reproductive health · 2022Review
- Monitoring of urinary arsenic (As) and lead (Pb) among a sample of pregnant Iranian women.Journal of environmental health science & engineering · 2021Article
- Definition and Multiple Factors of Recurrent Spontaneous Abortion.Advances in experimental medicine and biology · 2021Article
- Do pregnant women with anemia need iron supplementation?Journal of the Chinese Medical Association : JCMA · 2020Article
- Do healthy pregnant women need iron supplementation?Journal of the Chinese Medical Association : JCMA · 2020Article
- Is serum level of trace elements and heavy metals associated with threatened abortion?Journal of the Chinese Medical Association : JCMA · 2019Article
- Reply to: "Is serum level of trace elements and heavy metals associated with threatened abortion?"Journal of the Chinese Medical Association : JCMA · 2019Article
- Risk to increase threatened abortion: deficiency of some essential trace elements and exposure of toxic heavy metals.Journal of the Chinese Medical Association : JCMA · 2019Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backroundThis study aimed to investigate the impact of changes in the serum levels of trace elements and heavy metals in threatened abortion, which is a common complication in early pregnancy. Earlier studies have shown that changes in the serum levels of some trace elements and increased serum concentrations of heavy metals are associated with spontaneous abortion; however, this relationship has not been fully clarified.
methodsThe patient group consisted of 45 pregnant women diagnosed with threatened abortion. There were 40 healthy nonpregnant women in the control group. Blood samples were obtained from the patients and the healthy controls, and the concentrations of serum trace elements and heavy metals were measured using atomic absorption spectrophotometry.
resultsStatistically significant decreases were found in the serum zinc (Zn), iron (Fe), magnesium (Mg) and manganese (Mn) levels, and significant increases were found in the serum copper (Cu), cadmium (Cd) and lead (Pb) levels in cases of threatened abortion in comparison to the controls (p < 0.001). However, there was no difference between the groups in terms of the serum cobalt (Co) levels (p > 0.001).
conclusionChanges in the balance of some essential trace elements (especially decreases in Fe and Zn) and elevated concentrations of some toxic heavy metals in the blood may be important diagnostic and prognostic parameters for threatened abortion.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.