Evidence map›Paper›PMID 30892908›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2019

Cholecystokinin, gastrin, cholecystokinin/gastrin receptors, and bitter taste receptor TAS2R14: trophoblast expression and signaling.

Shèdy Taher, Yamilette Borja, Lucía Cabanela, Vincent J Costers, Morgan Carson-Marino, Julie C Bailes, Biswadeep Dhar, Mark T Beckworth, Maria B Rabaglino, Emiel D Post Uiterweer and 1 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Pharmacology of T2R Mediated Host-Microbe Interactions.Handbook of experimental pharmacology · 2022
    Article
  13. An update on extra-oral bitter taste receptors.Journal of translational medicine · 2021
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Shèdy TaherDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, and D. H. Barron Reproductive and Perinatal Biology Research Program, Gainesville, Florida.
Yamilette BorjaDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, and D. H. Barron Reproductive and Perinatal Biology Research Program, Gainesville, Florida.
Lucía CabanelaDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, and D. H. Barron Reproductive and Perinatal Biology Research Program, Gainesville, Florida.
Vincent J CostersDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, and D. H. Barron Reproductive and Perinatal Biology Research Program, Gainesville, Florida.
Morgan Carson-MarinoDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, and D. H. Barron Reproductive and Perinatal Biology Research Program, Gainesville, Florida.
Julie C BailesDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, and D. H. Barron Reproductive and Perinatal Biology Research Program, Gainesville, Florida.
Biswadeep DharDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, and D. H. Barron Reproductive and Perinatal Biology Research Program, Gainesville, Florida.
Mark T BeckworthDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, and D. H. Barron Reproductive and Perinatal Biology Research Program, Gainesville, Florida.
Maria B RabaglinoInstituto de Investigaciones en Ciencias de la Salud, Consejo Nacional de Investigaciones Científicas y Técnicas, Pabellón de Biología Celular, Córdoba , Argentina.
Emiel D Post UiterweerDepartment of Obstetrics and Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht , Utrecht , The Netherlands.
Kirk P ConradDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, and D. H. Barron Reproductive and Perinatal Biology Research Program, Gainesville, Florida.
University of Florida · USFlorida College · USConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity Medical Center Utrecht · NL

Funding

Project 4: Human Endometrial Programming for Successful ImplantationP50HD055764 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GIUDICE, LINDA C · 2014 to 2022
$16.4M
Trophoblast Differentiation in In Vivo and In Vitro Fertilized EmbryosU54HD055764 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SONG, JUN S · 2007 to 2013
$11.5M
Mechanisms & Consequences of Vascular Adaptations in Pregnancies Conceived by ARTP01HD065647 · NICHD · UNIVERSITY OF FLORIDA · PI CONRAD, KIRK P · 2011 to 2016
$6.1M
Short-Term Training in Biomedical Research for Under-Represented MinoritiesR25HL103181 · NHLBI · UNIVERSITY OF FLORIDA · PI WOOD, CHARLES E · 2010 to 2014
$591k
NHLBI NIH HHS R25 HL103181NICHD NIH HHS P01 HD065647NICHD NIH HHS P50 HD055764NICHD NIH HHS U54 HD055764
6 · The paper itself

Abstract

We investigated expression of cholecystokinin (CCK) in humans and mice, and the bitter taste receptor TAS2R14 in the human placenta. Because CCK and gastrin activate the CCKBR receptor, we also explored placental gastrin expression. Finally, we investigated calcium signaling by CCK and TAS2R14. By RT-PCR, we found

Indexed as

Signal TransductionAnimalsCalcium SignalingCell LineCholecystokininFemaleGastrinsGene Expression Regulation, DevelopmentalHumansLigandsMiceMice, Inbred C57BLPregnancyReceptor, Cholecystokinin BReceptors, CholecystokininReceptors, G-Protein-CoupledCholecystokininGastrinsLigandsReceptor, Cholecystokinin BReceptors, CholecystokininReceptors, G-Protein-CoupledRNA, MessengerTaste Receptors, Type 2extravillous trophoblastintracellular calciumplacentasyncytiotrophoblasttrophoblast glycogen cell

Identifiers

PMID30892908
PMCPMC6589605
OpenAlexW2922638990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.