Evidence map›Paper›PMID 30892752›Full record

ReviewJournal of neuroscience research2019

Methodological considerations for studies of brain glycogen.

Long Wu, Candance P Wong, Raymond A Swanson

Open access · greenAbstract readReview
In one paragraph

Review in Journal of neuroscience research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. The multifaceted roles of the brain glycogen.Journal of neurochemistry · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Long WuDepartment of Neurology, University of California, San Francisco, and San Francisco Veterans Affairs Health Care System, San Francisco, California.ORCID 0000-0003-1165-1784
Candance P WongDepartment of Neurology, University of California, San Francisco, and San Francisco Veterans Affairs Health Care System, San Francisco, California.
Raymond A SwansonDepartment of Neurology, University of California, San Francisco, and San Francisco Veterans Affairs Health Care System, San Francisco, California.ORCID 0000-0002-3664-5359
University of California, San Francisco · US

Funding

Integrating pathogenic mechanisms in Parkinson's diseaseR01NS105774 · NINDS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI SWANSON, RAYMOND A · 2018 to 2022
$1.8M
Thiol repletion therapy for Parkinson's diseaseI01BX003249 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI SWANSON, RAYMOND A · 2017 to 2020
–
BLRD VA I01 BX003249NINDS NIH HHS R01 NS105774
6 · The paper itself

Abstract

Glycogen stores in the brain have been recognized for decades, but the underlying physiological function of this energy reserve remains elusive. This uncertainty stems in part from several technical challenges inherent in the study of brain glycogen metabolism. These include low glycogen content in the brain, non-homogeneous labeling of glycogen by radiotracers, rapid glycogenolysis during postmortem tissue handling, and effects of the stress response on brain glycogen turnover. Here we briefly review the aspects of the glycogen structure and metabolism that bear on these technical challenges and present ways they can be addressed.

Indexed as

GlycogenolysisAnimalsBiological AssayBrainEnergy MetabolismGlycogenHistocytochemistryHumansGlycogenastrocytesenergy metabolismglycogen

Identifiers

PMID30892752
PMCPMC6565471
OpenAlexW2922694664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.