ArticleActa cirurgica brasileira2019
Ointment of Ximenes americana promotes acceleration of wound healing in rats1.
Article in Acta cirurgica brasileira, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- African Medicinal Plants in Cutaneous Wound Repair: A Comprehensive Analysis of the Role of Phytochemicals.International wound journal · 2025Review
- Medicinal plants used for cutaneous wound healing in Uganda; ethnomedicinal reports and pharmacological evidences.Heliyon · 2024Review
- Effects of the healing activity of rosemary-of-Chapada (Lippia gracilis Schauer) on cutaneous lesions in rats.Acta cirurgica brasileira · 2022Article
- Poly (Lactic Acid) membrane and Sedum dendroideum extract favors the repair of burns in rats.Acta cirurgica brasileira · 2020Article
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Authors and funding
6 authors.
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Abstract
purposeTo evaluate the healing potential of the Ximenia americana hydroalcoholic extract in 10% cream in excisional wound models in rats.
methodsSixty male adults Wistar rats were submitted to skin and subcutaneous tissue surgery in the right and left thoracic regions, divided into three experimental groups: Standard submitted to treatment with only the base vehicle, Treated wounds treated with hydroalcoholic extract of X. americana applied on 10%, Lanette base and Control, untreated wounds. The treatment was performed daily and the wounds evaluated microscopically by the quantification of fibroblasts, collagen fibers and blood vessels.
resultsThe histomorphometric analysis showed a significant increase in the number of fibroblasts, collagen fibers and blood vessels in the treated group.
conclusionThe topical action of the cream based on Ximenia americana shows angiogenic effects and improves the replacement of collagen, suggesting its use for the development of herbal remedy in the treatment of cutaneous wound healing.
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