ArticleNanoscale2019
Dynamic magnetic characterization and magnetic particle imaging enhancement of magnetic-gold core-shell nanoparticles.
Article in Nanoscale, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 50 citations in OpenAlex.
- Biomimetic membrane-coated metal nanoplatforms for enhanced BBB penetration and targeted glioblastoma therapy.International journal of pharmaceutics: X · 2026Review
- From Magnetic Moment to Magnetic Particle Imaging: A Comprehensive Review on MPI Technology, Tracer Design and Biological Applications.Pharmaceutics · 2026Review
- Metal-based nanomaterials achieve tumor treatment strategies by overcoming the blood-brain barrier of glioma and responding to the tumor microenvironment.Materials today. Bio · 2026Review
- On the effect of reference and sample volume on magnetic particle imaging quantification.Journal of magnetism and magnetic materials · 2025Article
- Advances in engineering nanoparticles for magnetic particle imaging (MPI).Science advances · 2025Review
- Magnetic Nanocomposite Hydrogels in Orthopedics: Applications and Perspectives.International journal of nanomedicine · 2025Review
- Analysis of Correlation Between Coronary Heart Disease and Genetic Polymorphism Detected by Gold Magnetic Nanoparticles Chromatography.Journal of cardiovascular translational research · 2024Article
- Post-synthesis Oxidation of Superparamagnetic Iron Oxide Nanoparticles to Enhance Magnetic Particle Imaging Performance.ACS applied nano materials · 2024Article
- Nanotechnology for brain tumor imaging and therapy based on π-conjugated materials: state-of-the-art advances and prospects.Frontiers in chemistry · 2023Review
- Indocyanine Green-Conjugated Superparamagnetic Iron Oxide Nanoworm for Multimodality Breast Cancer Imaging.ACS applied nano materials · 2022Article
- Metal-Based Nanostructured Therapeutic Strategies for Glioblastoma Treatment-An Update.Biomedicines · 2022Review
- Advanced Magnetic Resonance Imaging (MRI) Techniques: Technical Principles and Applications in Nanomedicine.Cancers · 2022Review
- Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy.Science advances · 2022Article
- Magnetism of Dendrimer-Coated Gold Nanoparticles: A Size and Functionalization Study.The journal of physical chemistry. C, Nanomaterials and interfaces · 2021Article
- Magnetic systems for cancer immunotherapy.Acta pharmaceutica Sinica. B · 2021Review
- The Effects of a Varied Gold Shell Thickness on Iron Oxide Nanoparticle Cores in Magnetic Manipulation, TNanomaterials (Basel, Switzerland) · 2020Article
- Magneto-plasmonic nanostars for image-guided and NIR-triggered drug delivery.Scientific reports · 2020Article
- Recent expansions of novel strategies towards the drug targeting into the brain.International journal of nanomedicine · 2019Review
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
Abstract
Multifunctional nanoparticles with a magnetic core and gold shell structures are emerging multi-modal imaging probes for disease diagnosis, image-guided therapy, and theranostic applications. Owing to their multi-functional magnetic and plasmonic properties, these nanoparticles can be used as contrast agents in multiple complementary imaging modalities. Magnetic particle imaging (MPI) is a new pre-clinical imaging system that enables real-time imaging with high sensitivity and spatial resolution by detecting the dynamic responses of nanoparticle tracers. In this study, we evaluated the dynamic magnetic properties and MPI imaging performances of core-shell nanoparticles with a magnetic core coated with a gold shell. A change in AC hysteresis loops was detected before and after the formation of the gold shell on magnetic core nanoparticles, suggesting the influence of the core-shell interfacial effect on their dynamic magnetic properties. This alteration in the dynamic responses resulted in an enhancement of the MPI imaging capacity of magnetic nanoparticles. The gold shell coating also enabled a simple and effective functionalization of the nanoparticles with a brain glioma targeting ligand. The enhanced MPI imaging capacity and effective functionality suggest the potential application of the magnetic-gold core-shell nanoparticles for MPI disease diagnostics.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.