Evidence map›Paper›PMID 30892277›Full record

ArticleAging2019

A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats.

Amelia K Pollard, Thomas L Ingram, Catharine A Ortori, Freya Shephard, Margaret Brown, Susan Liddell, David A Barrett, Lisa Chakrabarti

Open access · greenAbstract read
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  8. The dysregulatedAging · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Amelia K PollardSchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, LE12 5RD, UK.
Thomas L IngramSchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, LE12 5RD, UK.
Catharine A OrtoriCentre for Analytical Bioscience, School of Pharmacy University of Nottingham, NG7 2RD, UK.
Freya ShephardSchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, LE12 5RD, UK.
Margaret BrownWest Yorkshire Bat Hospital, Otley, West Yorkshire, LS21 1AJ, UK.
Susan LiddellSchool of Biosciences, University of Nottingham, Sutton Bonington, LE12 5RD, UK.
David A BarrettCentre for Analytical Bioscience, School of Pharmacy University of Nottingham, NG7 2RD, UK.
Lisa ChakrabartiSchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, LE12 5RD, UK.
University of Nottingham · GBWest Yorkshire Police · GB

Funding

Biotechnology and Biological Sciences Research Council BB/J014508/1
6 · The paper itself

Abstract

It is accepted that smaller mammals with higher metabolic rates have shorter lifespans. The very few species that do not follow these rules can give insights into interesting differences. The recorded maximum lifespans of bats are exceptional - over 40 years, compared with the laboratory mouse of 4 years. We investigated the differences in the biochemical composition of mitochondria between bat and mouse species. We used proteomics and ultra-high-performance liquid chromatography coupled with high resolution mass spectrometry lipidomics, to interrogate mitochondrial fractions prepared from

Indexed as

AgingAnimalsBrainCaenorhabditis elegansChiropteraFatty Acid Binding Protein 3LongevityMass SpectrometryMiceMitochondriaMuscle, SkeletalProteomeFatty Acid Binding Protein 3ProteomebatsFABP3free fatty acidlipidomicsmitochondriaproteomics

Identifiers

PMID30892277
PMCPMC6461166
OpenAlexW2924423411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.