Evidence map›Paper›PMID 30892182›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2019

A comparative analysis of prophylactic antimicrobial use in long-term care facilities in Ireland, 2013 and 2016.

Meera Tandan, Rory O'Connor, Karen Burns, Helen Murphy, Sarah Hennessy, Fiona Roche, Sheila Donlon, Martin Cormican, Akke Vellinga

Open access · diamondAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Meera TandanDiscipline of General Practice, School of Medicine, National University of Ireland Galway (NUIG), Galway, Ireland.
Rory O'ConnorDiscipline of Pharmacology, School of Medicine, National University of Ireland Galway (NUIG), Galway, Ireland.
Karen BurnsHealth Protection Surveillance Centre (HPSC), Dublin, Ireland.
Helen MurphyHealth Protection Surveillance Centre (HPSC), Dublin, Ireland.
Sarah HennessyHealth Protection Surveillance Centre (HPSC), Dublin, Ireland.
Fiona RocheHealth Protection Surveillance Centre (HPSC), Dublin, Ireland.
Sheila DonlonHealth Protection Surveillance Centre (HPSC), Dublin, Ireland.
Martin CormicanDiscipline of Bacteriology, School of Medicine, National University of Ireland Galway (NUIG), Galway, Ireland.
Akke VellingaDiscipline of General Practice, School of Medicine, National University of Ireland Galway (NUIG), Galway, Ireland.
Health Protection Surveillance Centre · IEOllscoil na Gaillimhe – University of Galway · IERoyal College of Surgeons in Ireland · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundLong-term care facilities (LTCFs) are important locations of antimicrobial consumption. Of particular concern is inappropriate prescribing of prophylactic antimicrobials. AimWe aimed to explore factors related to antimicrobial prophylaxis in LTCFs in Ireland. MethodsThe point prevalence surveys of Healthcare-Associated Infections in Long-Term Care Facilities (HALT) were performed in Ireland in May 2013 and 2016. Data were collected on facility (type and stewardship initiatives) and resident characteristics (age, sex, antimicrobial and indication) for those meeting the surveillance definition for a HAI and/or prescribed an antimicrobial. ResultsIn 2013, 9,318 residents (in 190 LTCFs) and in 2016, 10,044 residents (in 224 LTCFs) were included. Of the 10% of residents prescribed antimicrobials, 40% were on prophylaxis, most of which was to prevent urinary tract infection. The main prophylactic agents were: nitrofurantoin (39%) and trimethoprim (41%) for urinary tract (UT); macrolides (47%) for respiratory tract and macrolides and tetracycline (56%) for skin or wounds. More than 50% of the prophylaxis was prescribed in intellectual disability facilities and around 40% in nursing homes. Prophylaxis was recorded more often for females, residents living in LTCFs for more than 1 year and residents with a urinary catheter. No difference in prophylactic prescribing was observed when comparing LTCFs participating and not participating in both years. ConclusionsForty per cent of antimicrobial prescriptions in Irish LTCFs were prophylactic. This practice is not consistent with national antimicrobial prescribing guidelines. Addressing inappropriate prophylaxis prescribing in Irish LTCFs should be a key objective of antimicrobial stewardship initiatives.

Indexed as

Antimicrobial StewardshipAgedAged, 80 and overAnti-Bacterial AgentsAntibiotic ProphylaxisAnti-Infective AgentsCross InfectionDrug PrescriptionsFemaleHealth Care SurveysHomes for the AgedHumansInappropriate PrescribingIrelandLong-Term CareMaleAnti-Bacterial AgentsAnti-Infective Agentsantimicrobiallong-term care facilities, HALTprescribingprophylaxis

Identifiers

PMID30892182
PMCPMC6425550
OpenAlexW2921038099

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.