ArticleInfluenza and other respiratory viruses2019
Age-specific incidence rates and risk factors for respiratory syncytial virus-associated lower respiratory tract illness in cohort children under 5 years old in the Philippines.
Article in Influenza and other respiratory viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Incidence of respiratory syncytial virus infections among children in rural Bangladesh: a prospective observational study (2021-2023).The Lancet regional health. Southeast Asia · 2026Article
- Relating In Vivo Respiratory Syncytial Virus Infection Kinetics to Host Infectiousness in Different Age Groups.The Journal of infectious diseases · 2025Article
- Respiratory syncytial virus hospitalization costs, rates, and seasonality in Asia: a systematic review and meta-analysis.EClinicalMedicine · 2025Review
- Epidemiology and Diagnostic Accuracy of Respiratory Pathogens in Pediatric Populations: Insights From Global Studies.Cureus · 2024Review
- CD8Nature communications · 2024Article
- Respiratory syncytial virus-associated hospitalizations among children: an Italian retrospective observational study.Italian journal of pediatrics · 2024Observational
- Respiratory syncytial virus burden in children under 2 years old in understudied areas worldwide: gap analysis of available evidence, 2012-2022.Frontiers in pediatrics · 2024Review
- Article
- Resurgence of influenza and respiratory syncytial virus in Egypt following two years of decline during the COVID-19 pandemic: outpatient clinic survey of infants and children, October 2022.BMC public health · 2023Article
- Epidemiology and risk factors of respiratory syncytial virus associated acute respiratory tract infection in hospitalized children younger than 5 years from Sri Lanka.Frontiers in microbiology · 2023Article
- Respiratory syncytial virus-associated hospitalisation in children aged ≤5 years: a scoping review of literature from 2009 to 2021.ERJ open research · 2022Article
- Incidence of lower respiratory tract infection and associated viruses in a birth cohort in the Philippines.BMC infectious diseases · 2022Article
- Role of age and birth month in infants hospitalized with RSV-confirmed disease in the Valencia Region, Spain.Influenza and other respiratory viruses · 2022Article
- Risk of Transmission and Viral Shedding From the Time of Infection for Respiratory Syncytial Virus in Households.American journal of epidemiology · 2021Article
- Epidemiology and Seasonality of Childhood Respiratory Syncytial Virus Infections in the Tropics.Viruses · 2021Review
- Respiratory syncytial virus acute respiratory infection-associated hospitalizations in preterm Mexican infants: A cohort study.Influenza and other respiratory viruses · 2020Article
- Innate Immune Responses to Highly Pathogenic Coronaviruses and Other Significant Respiratory Viral Infections.Frontiers in immunology · 2020Review
- Age-specific incidence rates and risk factors for respiratory syncytial virus-associated lower respiratory tract illness in cohort children under 5 years old in the Philippines.Influenza and other respiratory viruses · 2019Article
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13 authors.
Funding
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Abstract
backgroundRespiratory syncytial virus (RSV) is one of the main viral causes of lower respiratory tract illness (LRTI), especially in young children. RSV vaccines, including maternal and infant vaccines, are under development; however, more epidemiological studies are needed to develop effective vaccination strategies.
objectivesTo estimate detailed age-specific incidence rates and severity of RSV-associated LRTI (RSV-LRTI) using data from a community-based prospective cohort study in the Philippines. PATIENTS/
methodsCohort children who visited health facilities due to acute respiratory symptoms were identified, and nasopharyngeal swabs were collected to detect RSV. The severity of RSV-LRTI was assessed using the severity definition proposed by the World Health Organization. Risk factors for developing RSV-LRTI and contribution of SpO
resultsA total of 395 RSV episodes which occurred in children aged 2-59 months were categorised as 183 RSV-LRTI, 72 as severe RSV-LRTI and 29 as very severe RSV-LRTI. Children aged 3-5 months had the highest incidence rate of RSV-LRTI, at 207.4 per 1000 child-years (95% CI: 149.0-279.5). Younger age group, place of living and low educational level of caregivers were associated with developing RSV-LRTI. Clinical manifestations had low levels of agreement with hypoxaemia as measured by pulse oximeter.
conclusionThe highest burden of RSV was observed in young infants aged 3-5 months, whereas the burden was also high in those aged 12-20 months. Future vaccination strategies should consider the protection of older children, especially those aged one year, as well as young infants.
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