Evidence map›Paper›PMID 30891834›Full record

ArticleJournal of clinical periodontology2019

Development and validation of a predictive model for periodontitis using NHANES 2011-2012 data.

Eduardo Montero, David Herrera, Mariano Sanz, Sangeeta Dhir, Thomas Van Dyke, Corneliu Sima

Abstract read
In one paragraph

Article in Journal of clinical periodontology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  6. Occurrence ofMicroorganisms · 2024
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  9. Association between the presence and genotype ofExperimental and therapeutic medicine · 2023
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  14. Periodontal Health and Use of Oral Health Services: A Comparison of Germans and Two Migrant Groups.International journal of environmental research and public health · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eduardo MonteroETEP (Etiology and Therapy of Periodontal Diseases) Research Group, University Complutense, Madrid, Spain.ORCID 0000-0003-2525-8529
David HerreraETEP (Etiology and Therapy of Periodontal Diseases) Research Group, University Complutense, Madrid, Spain.
Mariano SanzETEP (Etiology and Therapy of Periodontal Diseases) Research Group, University Complutense, Madrid, Spain.
Sangeeta DhirDepartment of Dentistry. Consultant Periodontist, Max Super Specialty Hospital, Saket, New Delhi, India.
Thomas Van DykeCenter for Clinical and Translational Research, Forsyth Institute, Cambridge, Massachusetts.
Corneliu SimaCenter for Clinical and Translational Research, Forsyth Institute, Cambridge, Massachusetts.ORCID 0000-0003-3526-4850

Funding

Mechanisms of Resolvin E1 in Periodontal RegenerationR01DE025020 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI VAN DYKE, THOMAS ELLIOTT · 2015 to 2023
$4.9M
Regulation of Inflammation in T2D-Associated PeriodontitisR00DE024575 · NIDCR · HARVARD MEDICAL SCHOOL · PI SIMA, CORNELIU · 2018 to 2020
$725k
M1/M2 Regulation of Inflammation in T2D-Associated PeriodontitisK99DE024575 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI SIMA, CORNELIU · 2015 to 2016
$244k
NIDCR NIH HHS K99 DE024575NIDCR NIH HHS R00 DE024575NIDCR NIH HHS R01 DE025020
6 · The paper itself

Abstract

aimTo develop and validate a predictive model for moderate-to-severe periodontitis in the adult USA population, with data from the 2011-2012 National Health and Nutrition Examination Survey (NHANES) cycle. MATERIAL AND

methodsA subset of 3017 subjects aged >30 years, with >14 teeth present and having received a periodontal examination in addition to data collected on cardio-metabolic risk measures (smoking habit, body mass index [BMI], blood pressure, total cholesterol and glycated haemoglobin [HbA1c]) were used for model development by multivariable logistic regression.

resultsThe prevalence of moderate and severe periodontitis using CDC/AAP classification was 37.1% and 13.2%, respectively. A multivariable logistic regression model revealed that HbA1c ≥5.7% was significantly associated with moderate-to-severe periodontitis (odds ratio, OR = 1.29; p < 0.01). A predictive model including age, gender, ethnicity, HbA1c and smoking habit as variables had 70.0% sensitivity and 67.6% specificity in detecting moderate-to-severe periodontitis in US adults.

conclusionsPeriodontitis is a common disease in North American adults, and its prevalence is significantly higher in individuals with pre-diabetes or diabetes. The present study demonstrates that a model including age, gender, ethnicity, HbA1c and smoking habit could be used as a reliable screening tool for periodontitis in primary medical care settings to facilitate referral of patients at risk for periodontal examination and diagnosis.

Indexed as

Nutrition SurveysPeriodontitisAdultGlycated HemoglobinHumansPrevalenceSmokingGlycated Hemoglobindiabetesendocrinologyglycated haemoglobinHbA1cperiodontitispredictive modelling

Identifiers

PMID30891834
PMCPMC7050186

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.