Evidence map›Paper›PMID 30891811›Full record

ReviewAllergy2019

Innate immunity in allergy.

Kazuhiko Maeda, Matias J Caldez, Shizuo Akira

Abstract readReview
In one paragraph

Review in Allergy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Selenium biofortification: integrating one health and sustainability.Journal of the science of food and agriculture · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Microorganisms · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kazuhiko MaedaLaboratory of Host Defense, The World Premier International Research Center Initiative (WPI) Immunology Frontier Research Center (IFReC), Osaka University, Osaka, Japan.ORCID 0000-0003-0305-8163
Matias J CaldezLaboratory of Host Defense, The World Premier International Research Center Initiative (WPI) Immunology Frontier Research Center (IFReC), Osaka University, Osaka, Japan.ORCID 0000-0002-2123-8486
Shizuo AkiraLaboratory of Host Defense, The World Premier International Research Center Initiative (WPI) Immunology Frontier Research Center (IFReC), Osaka University, Osaka, Japan.ORCID 0000-0001-7602-9617

Funding

Japan Society for the Promotion of Science 15H05704Japan Society for the Promotion of Science 18K07173
6 · The paper itself

Abstract

Innate immune system quickly responds to invasion of microbes and foreign substances through the extracellular and intracellular sensing receptors, which recognize distinctive molecular and structural patterns. The recognition of innate immune receptors leads to the induction of inflammatory and adaptive immune responses by activating downstream signaling pathways. Allergy is an immune-related disease and results from a hypersensitive immune response to harmless substances in the environment. However, less is known about the activation of innate immunity during exposure to allergens. New insights into the innate immune system by sensors and their signaling cascades provide us with more important clues and a framework for understanding allergy disorders. In this review, we will focus on recent advances in the innate immune sensing system.

Indexed as

Immunity, InnateAdaptive ImmunityAdaptor Proteins, Signal TransducingAnimalsDisease SusceptibilityHumansHypersensitivityInflammasomesLectins, C-TypeNF-kappa BNLR ProteinsProtein KinasesReceptors, Pattern RecognitionSignal TransductionTh2 CellsToll-Like ReceptorsAdaptor Proteins, Signal TransducingALPK1 protein, humanInflammasomesLectins, C-TypeNF-kappa BNLR ProteinsProtein KinasesReceptors, Pattern RecognitionTIFA protein, humanToll-Like Receptorsinflammasomepattern recognition receptorspyroptosis

Identifiers

PMID30891811
PMCPMC6790574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.