Observational studyJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2020
Early Systemic Inflammatory Response Syndrome Duration Predicts Infected Pancreatic Necrosis.
Observational study in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Age-related vulnerability and clinical outcomes in acute pancreatitis: a stratified cohort study of 1,034 patients.BMC gastroenterology · 2026Article
- Comparison of clinical outcomes between non-invasive ventilation and high-flow nasal cannula use in patients with acute pancreatitis.BMC pulmonary medicine · 2026Article
- Development and validation of a 24-h predictive model for hypertriglyceridemic moderately severe acute pancreatitis: a single-center retrospective study.Frontiers in medicine · 2026Article
- Automated machine learning for early prediction of systemic inflammatory response syndrome in acute pancreatitis.BMC medical informatics and decision making · 2025Article
- Approach to the Diagnosis and Management of Infected Pancreatic Necrosis: A Narrative Review.Cureus · 2025Review
- Early prediction and prevention of infected pancreatic necrosis.World journal of gastroenterology · 2024Article
- Prediction of infected pancreatic necrosis in acute necrotizing pancreatitis by the modified pancreatitis activity scoring system.United European gastroenterology journal · 2023Article
- Characteristics and Incidence of Colon Complication in Necrotizing pancreatitis: A Propensity Score-Matched Study.Journal of inflammation research · 2023Article
- A Clinic-Radiomics Model for Predicting the Incidence of Persistent Organ Failure in Patients with Acute Necrotizing Pancreatitis.Gastroenterology research and practice · 2023Article
- Blood Urea Nitrogen as a Prognostic Marker in Severe Acute Pancreatitis.Disease markers · 2022Article
- Risk Factors and Outcomes of Multidrug-Resistant Bacteria Infection in Infected Pancreatic Necrosis Patients.Infection and drug resistance · 2022Article
- How to Identify the Indications for Early Intervention in Acute Necrotizing Pancreatitis Patients: A Long-Term Follow-Up Study.Frontiers in surgery · 2022Article
- Hyperhomocysteinemia Associated with Multiple Organ Failure in Acute Pancreatitis Patients.BioMed research international · 2020Article
- Management of Severe Acute Pancreatitis.Current treatment options in gastroenterology · 2020Review
- Irisin attenuates intestinal injury, oxidative and endoplasmic reticulum stress in mice with L-arginine-induced acute pancreatitis.World journal of gastroenterology · 2019Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeSystemic inflammatory response syndrome (SIRS) was considered to play an important role in the progress of acute pancreatitis, but its specific relation with infected pancreatic necrosis remains largely unclear. We aimed to investigate the correlation between SIRS duration and infected pancreatic necrosis, and its application in prediction of infected pancreatic necrosis.
methodsA prospective observational cohort study of 2130 patients with acute pancreatitis from 2012 to 2017. The SIRS duration at the first week was registered daily, and demographic, radiology, and all clinical laboratory data were prospectively collected and retrospectively reviewed.
resultsA significant upward tendency of infected pancreatic necrosis incidence was observed with increased SIRS duration. In multivariate logistic regression, SIRS duration (odds ratio, 1.305; 95% CI, 1.161-1.468) was independently associated with infected pancreatic necrosis. ROC analysis demonstrated that the areas under curves of SIRS duration for predicting persistent multi-organ failure, pancreatic infection, and mortality were 0.97 (95% CI, 0.96-0.98), 0.92 (95% CI, 0.91-0.94), and 0.86 (95% CI, 0.83-0.90), respectively, which were comparable to, or even greater than, the area under curves of APACHE II and CT severity index scores.
conclusionsEarly SIRS duration was strongly associated with infected pancreatic necrosis and could serve as an easy bedside indicator to predict pancreatic infection.
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