ArticleAnimal models and experimental medicine2018
Evaluation of an ischemic model in ischemia prone and general Mongolian gerbils by neurological symptom, injury, and sex difference.
Article in Animal models and experimental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Development of a new cerebral ischemia reperfusion model of Mongolian gerbils and standardized evaluation system.Animal models and experimental medicine · 2024Article
- CHIP ameliorates neuronal damage in HScientific reports · 2022Article
- Article
- Evaluation of an ischemic model in ischemia prone and general Mongolian gerbils by neurological symptom, injury, and sex difference.Animal models and experimental medicine · 2018Article
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8 authors.
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Abstract
backgroundIn the previous study, we established an ischemia-prone gerbil population (IG), which was selectively bred to increase the incidence of unilateral carotid arterial occlusion (UCO)-induced ischemia in Mongolian gerbils. However, if the characteristics of ischemia model in IG are the same as those in general gerbils (GG), and if the neurological symptoms are associated with the neurological insults in IG is still unclear.
methodsIn the present study, we evaluated the UCO model in IG by analyzing neurological symptoms, neurological injury in the hippocampal CA1 region and compared with GG.
resultsThe data showed that the ratios of neurological symptom scores ≥ 2 in the IG and GG groups were 65.0% vs 30.0%, respectively, and were significantly different (
conclusionOur findings suggest that IG population would likely be more advantageous to establish an ischemic model.
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