ArticleJournal of medical imaging (Bellingham, Wash.)2019
Initial evaluation of three-dimensionally printed patient-specific coronary phantoms for CT-FFR software validation.
Article in Journal of medical imaging (Bellingham, Wash.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03149042 (Validation of a Computed Tomography), which is not on this map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validation of a Computed Tomography (CT) Based Fractional Flow Reserve (FFR) Software Using the 320 Detector Aquilion ONE CT Scanner.
Who cites it
7 citing papers in PubMed.
- Quality assurance of 3D-printed patient specific anatomical models: a systematic review.3D printing in medicine · 2024Article
- Development of Custom Wall-Less Cardiovascular Flow Phantoms with Tissue-Mimicking Gel.Cardiovascular engineering and technology · 2022Article
- Use of patient specific 3D printed neurovascular phantoms to simulate mechanical thrombectomy.3D printing in medicine · 2021Article
- Compliant vascular models 3D printed with the Stratasys J750: a direct characterization of model distensibility using intravascular ultrasound.3D printing in medicine · 2021Article
- Evaluation of challenges and limitations of mechanical thrombectomy using 3D printed neurovascular phantoms.Proceedings of SPIE--the International Society for Optical Engineering · 2021Article
- Clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: adult cardiac conditions.3D printing in medicine · 2020Article
- Method to simulate distal flow resistance in coronary arteries in 3D printed patient specific coronary models.3D printing in medicine · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We developed three-dimensionally (3D) printed patient-specific coronary phantoms that are capable of sustaining physiological flow and pressure conditions. We assessed the accuracy of these phantoms from coronary CT acquisition, benchtop experimentation, and CT-FFR software. Five patients with coronary artery disease underwent 320-detector row coronary CT angiography (CCTA) (Aquilion ONE, Canon Medical Systems) and a catheter lab procedure to measure fractional flow reserve (FFR). The aortic root and three main coronary arteries were segmented (Vitrea, Vital Images) and 3D printed (Eden 260V, Stratasys). Phantoms were connected into a pulsatile flow loop, which replicated physiological flow and pressure gradients. Contrast was introduced and the phantoms were scanned using the same CT scanner model and CCTA protocol as used for the patients. Image data from the phantoms were input to a CT-FFR research software (Canon Medical Systems) and compared to those derived from the clinical data, along with comparisons between image measurements and benchtop FFR results. Phantom diameter measurements were within 1 mm on average compared to patient measurements. Patient and phantom CT-FFR results had an absolute mean difference of 4.34% and Pearson correlation of 0.95. We have demonstrated the capabilities of 3D printed patient-specific phantoms in a diagnostic software.
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Registered trials
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