Evidence map›Paper›PMID 30891458›Full record

SynthesisBioMed research international2019

A Systematic Review of Potential Therapeutic Use of Lycium Barbarum Polysaccharides in Disease.

Sum Sum Kwok, Yashan Bu, Amy Cheuk-Yin Lo, Tommy Chung-Yan Chan, Kwok Fai So, Jimmy Shiu-Ming Lai, Kendrick Co Shih

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. A Structurally CharacterizedAntioxidants (Basel, Switzerland) · 2026
    Article
  4. Dual-Species Fermentation of aFoods (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. The Beneficial Effect ofAnalytical cellular pathology (Amsterdam) · 2025
    Article
  11. Antitumor Mechanisms ofLife (Basel, Switzerland) · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Ciabatta Bread Incorporating Goji (Foods (Basel, Switzerland) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sum Sum KwokDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.ORCID 0000-0002-1826-5467
Yashan BuDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.
Amy Cheuk-Yin LoDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.ORCID 0000-0003-4239-6851
Tommy Chung-Yan ChanDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.ORCID 0000-0003-4228-9482
Kwok Fai SoDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.ORCID 0000-0003-4039-4246
Jimmy Shiu-Ming LaiDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.ORCID 0000-0002-1367-6953
Kendrick Co ShihDepartment of Ophthalmology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong.ORCID 0000-0001-6255-2941
University of Hong Kong · HKHong Kong Sanatorium and Hospital · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of

methodsWe performed an Entrez PubMed literature search using keywords "lycium", "barbarum", "polysaccharides", "anti-fibrotic", "anti-apoptotic", "anti-oxidizing", "anti-aging", "neuroprotection", "metabolism", "diabetes", "hyperlipidemia", "neuroprotection", and "immunomodulation" on the 14

resultsThe 20 selected papers included 2 randomized control trials (1 double-blinded RCT and 1 double-blinded placebo-controlled RCT), 11 in vivo studies, 5 in vitro studies, 1 study with both in vivo and in vitro results, and 1 chemical study. There is good evidence from existing studies on the antifibrotic, antioxidizing, neuroprotective, anticancer, and anti-inflammatory effects of

conclusionResults from existing studies suggest that LBP is a promising therapeutic agent, particularly in the management of liver disease, hyperlipidemia, and diabetes. One major limitation of current research is a lack of standardization and quality control for the LBP used. The availability of research-grade LBP will inevitably promote future research in this field worldwide.

Indexed as

DiseaseAnimalsAntineoplastic AgentsDrugs, Chinese HerbalHumansNeuroprotective AgentsTranslational Research, BiomedicalAntineoplastic AgentsDrugs, Chinese Herballycium barbarum polysaccharideNeuroprotective Agents

Identifiers

PMID30891458
PMCPMC6390233
OpenAlexW2911905521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.