Evidence map›Paper›PMID 30891432›Full record

ArticleFrontiers in cellular and infection microbiology2019

The Activin Receptor, Activin-Like Kinase 4, Mediates

Agnieszka Lis, Mandi Wiley, Joan Vaughan, Peter C Gray, Ira J Blader

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Agnieszka LisDepartment of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, United States.
Mandi WileyDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.
Joan VaughanSalk Institute, La Jolla, CA, United States.
Peter C GraySalk Institute, La Jolla, CA, United States.
Ira J BladerDepartment of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, United States.
Salk Institute for Biological Studies · USUniversity at Buffalo, State University of New York · USUniversity of Oklahoma Health Sciences Center · US

Funding

CONTROL OF TOXOPLASMA GONDII GROWTH BY THE HOST CELL TRANSCRIPTION FACTOR HIF1R01AI069986 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI BLADER, IRA J · 2006 to 2021
$5.7M
NIAID NIH HHS R01 AI069986
6 · The paper itself

Abstract

To grow and cause disease, intracellular pathogens modulate host cell processes. Identifying these processes as well as the mechanisms used by the pathogens to manipulate them is important for the development of more effective therapeutics. As an example, the intracellular parasite

Indexed as

Host-Pathogen InteractionsActivin Receptors, Type IAnimalsCells, CulturedHumansHypoxia-Inducible Factor 1MiceToxoplasmaActivin Receptors, Type IACVR1B protein, humanHypoxia-Inducible Factor 1hypoxiaparasite - host interactionstgf-beta signalingtoxoplasma and toxoplasmosistranscripional regulation

Identifiers

PMID30891432
PMCPMC6411701
OpenAlexW2914950666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.