Evidence map›Paper›PMID 30891344›Full record

ArticleBiomedical optics express2019

Rapid pathology of lumpectomy margins with open-top light-sheet (OTLS) microscopy.

Ye Chen, Weisi Xie, Adam K Glaser, Nicholas P Reder, Chenyi Mao, Suzanne M Dintzis, Joshua C Vaughan, Jonathan T C Liu

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
10.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Assessing the Effects of a 3-Dimensional (3D) Pathology Tissue-Processing Workflow on Downstream Molecular Analyses.Laboratory investigation; a journal of technical methods and pathology · 2026
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  15. An end-to-end workflow for non-destructive 3D pathology.bioRxiv : the preprint server for biology · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Intraoperative imaging in pathology-assisted surgery.Nature biomedical engineering · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ye ChenDepartment of Mechanical Engineering, University of Washington, Seattle, WA 98195, USA.
Weisi XieDepartment of Mechanical Engineering, University of Washington, Seattle, WA 98195, USA.
Adam K GlaserDepartment of Mechanical Engineering, University of Washington, Seattle, WA 98195, USA.
Nicholas P RederDepartment of Pathology, University of Washington School of Medicine, Seattle, WA 98195, USA.
Chenyi MaoDepartment of Chemistry, University of Washington Seattle, WA 98195, USA.
Suzanne M DintzisDepartment of Pathology, University of Washington School of Medicine, Seattle, WA 98195, USA.
Joshua C VaughanDepartment of Chemistry, University of Washington Seattle, WA 98195, USA.
Jonathan T C LiuDepartment of Mechanical Engineering, University of Washington, Seattle, WA 98195, USA.
University of Washington · US

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
Coordinating and Bioinformatics Unit for the MMPC/DiaCompU24DK076169 · NIDDK · AUGUSTA UNIVERSITY · PI MCINDOE, RICHARD A. · 2006 to 2018
$42.4M
Coordinating Unit for DiaCompU24DK115255 · NIDDK · AUGUSTA UNIVERSITY · PI MCINDOE, RICHARD A. · 2017 to 2020
$11.6M
Line-scanned MEMS-based dual-axis confocal microscopy to detect oral lesions in vR01DE023497 · NIDCR · UNIVERSITY OF WASHINGTON · PI LIU, JONATHAN T.C. · 2012 to 2014
$2.4M
Intraoperative confocal microscopy for quantitative delineation of low-grade glioR01CA175391 · NCI · UNIVERSITY OF WASHINGTON · PI LIU, JONATHAN T.C., SANAI, NADER · 2014 to 2018
$1.7M
Light-sheet microscopy (LSM) for rapid wide-area imaging and pathology of bread-loafed prostate specimensF32CA213615 · NCI · UNIVERSITY OF WASHINGTON · PI GLASER, ADAM K · 2017 to 2019
$134k
NCI NIH HHS F32 CA213615NCI NIH HHS P30 CA015704NCI NIH HHS R01 CA175391NIDCR NIH HHS R01 DE023497NIDDK NIH HHS U24 DK076169NIDDK NIH HHS U24 DK115255
6 · The paper itself

Abstract

Open-top light-sheet microscopy is a technique that can potentially enable rapid

Identifiers

PMID30891344
PMCPMC6420271
OpenAlexW2916387552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.