ArticleBiomedical optics express2019
Label-free self-referenced sensing of living cells by terahertz metamaterial-based reflection spectroscopy.
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- The theory, technology, and application of terahertz metamaterial biosensors: A review.Fundamental research · 2025Review
- Study on an artificial phenomenon observed in terahertz biological imaging.Biomedical optics express · 2021Article
- Terahertz polarization sensing based on metasurface microsensor display anti-proliferation of tumor cells with aspirin.Biomedical optics express · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
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Abstract
Terahertz (THz) metamaterial-based reflection spectroscopy is proposed for label-free sensing of living cells by a self-referenced method. When sensing the living Madin-Darby canine kidney cell monolayer and phosphate buffered saline solution, self-referenced signals showed significant differences in peak intensity because of inherent discrepancy in the imaginary part of their complex refractive indices, as confirmed by 3D-FDTD simulations. The resonance peak intensity was unaffected by cell monolayer thickness variation, demonstrating feasibility for sensing various cells. Simulations and experiments showed that saponin-induced changes in cell permeability could be monitored in real-time. The self-referenced signal was linearly dependent on the adherent cell density, illustrating a label-free
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