Evidence map›Paper›PMID 30891159›Full record

ArticleJournal of oral microbiology2019

Caries-associated oral microbiome in head and neck cancer radiation patients: a longitudinal study.

Jean-Luc C Mougeot, Craig B Stevens, Kathryn G Almon, Bruce J Paster, Rajesh V Lalla, Michael T Brennan, Farah Bahrani Mougeot

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of oral microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02057510 (Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02057510 completednot on this map

Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients

Typeobservational_patient_registrySponsorWake Forest University Health SciencesRan2014 to 2020Enrolled613ConditionsHead and Neck Cancer, Dental Disease, Xerostomia, Osteoradionecrosis
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Oral microbiota associated with radiation-related caries among nasopharyngeal carcinoma patients following radiation therapy: analysis based on a longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Microbial dysbiosis in oral cavity determines obesity status in adolescents.Cellular and molecular life sciences : CMLS · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Chronic Oral Complications of Oral Cancer Therapy.Dental clinics of North America · 2025
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jean-Luc C MougeotCarolinas Medical Center - Atrium Health, Charlotte, NC, USA.
Craig B StevensCarolinas Medical Center - Atrium Health, Charlotte, NC, USA.
Kathryn G AlmonCarolinas Medical Center - Atrium Health, Charlotte, NC, USA.ORCID 0000-0002-0103-9877
Bruce J PasterThe Forsyth Institute, Cambridge, MA, USA.
Rajesh V LallaUniversity of Connecticut Health, Farmington, CT, USA.
Michael T BrennanCarolinas Medical Center - Atrium Health, Charlotte, NC, USA.
Farah Bahrani MougeotCarolinas Medical Center - Atrium Health, Charlotte, NC, USA.
Carolinas Medical Center · USUConn Health · US

Funding

Long-term Oral Complications of an Established Head and Neck Cancer Cohort- Clinical Registry of Dental Outcomes in Head and Neck Cancer Patients: OraRadU01DE022939 · NIDCR · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRENNAN, MICHAEL T, LALLA, RAJESH V. · 2012 to 2023
$16.8M
NIDCR NIH HHS U01 DE022939
6 · The paper itself

Abstract

Head and neck cancer (HNC) therapy often leads to caries development. Our goal was to characterize the oral microbiome of HNC patients who underwent radiation therapy (RT) at baseline (T0), and 6 (T6) and 18 (T18) months post-RT, and to determine if there was a relationship with increased caries. HOMI

Indexed as

16S rRNAcariesHead and neck cancermicrobiomenext generation sequencingradiation therapy

Identifiers

PMID30891159
PMCPMC6419625
OpenAlexW2921939508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.