Evidence map›Paper›PMID 30891100›Full record

ArticleBehavioural neurology2019

A Repeated Measures Pilot Comparison of Trajectories of Fluctuating Endogenous Hormones in Young Women with Traumatic Brain Injury, Healthy Controls.

Janet P Niemeier, Paul B Perrin, Bradley S Hurst, David M Foureau, Toan T Huynh, Susan L Evans, Jonathan E Silverman, M Elise McClannahan, Benjamin D Brusch, Mark Newman and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Behavioural neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Janet P NiemeierCarolinas Medical Center, Charlotte, NC, USA.
Paul B PerrinDepartment of Psychology, Virginia Commonwealth University, Richmond, VA, USA.ORCID 0000-0003-2070-215X
Bradley S HurstCarolinas Medical Center, Charlotte, NC, USA.
David M FoureauCarolinas Medical Center, Charlotte, NC, USA.
Toan T HuynhCarolinas Medical Center, Charlotte, NC, USA.
Susan L EvansCarolinas Medical Center, Charlotte, NC, USA.
Jonathan E SilvermanCarolinas Medical Center, Charlotte, NC, USA.
M Elise McClannahanCarolinas Medical Center, Charlotte, NC, USA.
Benjamin D BruschCarolinas Medical Center, Charlotte, NC, USA.
Mark NewmanCarolinas Medical Center, Charlotte, NC, USA.
Jean-Luc MougeotCarolinas Medical Center, Charlotte, NC, USA.
Amy K WagnerDepartment of Physical Medicine and Rehabilitation, University of Pittsburgh, PA, USA.
Carolinas Medical Center · USUniversity of Pittsburgh · USVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare baseline and 72-hour hormone levels in women with traumatic brain injury (TBI) and controls.

settingHospital emergency department.

participants21 women ages 18-35 with TBI and 21 controls.

designRepeated measures. MAIN MEASURES: Serum samples at baseline and 72 hours; immunoassays for estradiol (E2), progesterone (PRO), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and cortisol (CORT); and health history.

resultsWomen with TBI had lower E2 (

conclusionAcute TBI may suppress E2 and increase CORT in young women. OCs appeared to independently affect CORT and FSH responses. Future work is needed with a larger sample to characterize TBI effects on women's endogenous hormone response to injury and OC use's effects on post-TBI stress response and gonadal function, as well as secondary injury.

Indexed as

Age FactorsAdolescentAdultBrain InjuriesBrain Injuries, TraumaticEstradiolFemaleFollicle Stimulating HormoneHumansLuteinizing HormoneProgesteroneYoung AdultEstradiolFollicle Stimulating HormoneLuteinizing HormoneProgesterone

Identifiers

PMID30891100
PMCPMC6390250
OpenAlexW2914352247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.