Evidence map›Paper›PMID 30891078›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

Effect of Puerarin, Baicalin and Berberine Hydrochloride on the Regulation of IPEC-J2 Cells Infected with Enterotoxigenic

Xiaoxi Liu, Fenghua Liu, Yunfei Ma, Huanrong Li, Xianghong Ju, Jianqin Xu

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Flavonoids fromInternational journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Berberine alleviates enterotoxigenicFrontiers in nutrition · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Berberine Inhibits the Adhesion ofFrontiers in pharmacology · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiaoxi LiuChina Agricultural University-Beijing University of Agriculture Traditional Chinese Veterinary Medicine Teaching and Research Team, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Fenghua LiuBeijing Key Laboratory for Dairy Cow Nutrition, College of Animal Science and Technology, Beijing University of Agriculture, Beijing 102200, China.ORCID 0000-0001-7713-8604
Yunfei MaChina Agricultural University-Beijing University of Agriculture Traditional Chinese Veterinary Medicine Teaching and Research Team, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-6176-3496
Huanrong LiBeijing Key Laboratory for Dairy Cow Nutrition, College of Animal Science and Technology, Beijing University of Agriculture, Beijing 102200, China.
Xianghong JuDepartment of Veterinary Medicine, Guangdong Ocean University, Zhanjiang 524088, China.
Jianqin XuChina Agricultural University-Beijing University of Agriculture Traditional Chinese Veterinary Medicine Teaching and Research Team, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-7941-573X
Beijing University of Agriculture · CNGuangdong Ocean University · CN

Funding

Validation of methods for detection of Campylobacter in veterinary patientsU18FD005013 · FDA · TEXAS A&M AGRILIFE RESEARCH · PI LAWHON, SARA D., SUCHODOLSKI, JAN · 2013 to 2015
$278k
FDA HHS U18 FD005013
6 · The paper itself

Abstract

Puerarin, baicalin and berberine hydrochloride are the main components of Gegen Qinlian Decoction, which has been used to treat diarrhoea in China for hundreds of years, yet the biological function and molecular mechanism of these components are not clear. To investigate the effects of puerarin, baicalin, and berberine hydrochloride on the regulation of porcine intestinal epithelial cells (IPEC-J2 cells) infected with enterotoxigenic

Identifiers

PMID30891078
PMCPMC6390247
OpenAlexW2911782743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.