Evidence map›Paper›PMID 30891044›Full record

ReviewFrontiers in immunology2019

Leukocyte Trafficking and Regulation of Murine Hematopoietic Stem Cells and Their Niches.

Daniel Lucas

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Cellular crosstalk in the bone marrow niche.Journal of translational medicine · 2024
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Foxp3Frontiers in endocrinology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Daniel LucasDivision of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
Cincinnati Children's Hospital Medical Center · US

Funding

Role of Hox Genes in Integration of the Musculoskeletal System in Development R01AR061402 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI WELLIK, DENEEN M · 2011 to 2021
$3.3M
Cellular crosstalk in the hematopoietic microenvironmentR01HL136529 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI LUCAS, DANIEL · 2018 to 2021
$1.6M
NHLBI NIH HHS R01 HL136529NIAMS NIH HHS R01 AR061402
6 · The paper itself

Abstract

Hematopoietic stem cells (HSC) are the most powerful type of adult stem cell found in the body. Hematopoietic stem cells are multipotent and capable of giving rise to all other types of hematopoietic cells found in the organism. A single HSC is capable of regenerating a functional hematopoietic system when transplanted into a recipient. Hematopoietic stem cells reside in the bone marrow in specific multicellular structures called niches. These niches are indispensable for maintaining and regulating HSC numbers and function. It has become increasingly clearer that HSC and their niches can also be regulated by migrating leukocytes. Here we will discuss the composition of murine bone marrow niches and how HSC and their niches are regulated by different types of leukocytes that traffic between the periphery and the niche. Unless otherwise indicated all the studies discussed below were performed in mouse models.

Indexed as

AnimalsBone MarrowCell MovementEndothelial Progenitor CellsHematopoietic Stem CellsLeukocytesMacrophagesMiceStem Cell NicheStromal Cellshematopoietic stem cellleukocyte traffickingneutrophilsnichesTregs

Identifiers

PMID30891044
PMCPMC6412148
OpenAlexW2920111808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.