ArticleFrontiers in immunology2019
Variability in German Cockroach Extract Composition Greatly Impacts T Cell Potency in Cockroach-Allergic Donors.
Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Cockroach immunotherapy modulates dominant T-cell responses independent of allergen extract content.The Journal of allergy and clinical immunology · 2025Trial
- Cockroach gut microbiota is a significant source of endotoxin, a risk factor for asthma in cockroach-infested homes.Journal of medical entomology · 2026Article
- Allergic Asthma in Children: The Hidden Role of Cockroaches.Pediatric pulmonology · 2025Article
- Identification of cow milk epitopes to characterize and quantify disease-specific T cells in allergic children.The Journal of allergy and clinical immunology · 2023Article
- Cockroach allergy: Understanding complex immune responses to develop novel therapies.Molecular immunology · 2023Article
- Ampicillin treated German cockroach extract leads to reduced inflammation in human lung cells and a mouse model of Asthma.Parasites, hosts and diseases · 2023Article
- Article
- Detection and Enumeration of Cytokine-Secreting Cells by FluoroSpot.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children.Clinical and translational allergy · 2021Article
- HLA-DR Marks Recently Divided Antigen-Specific Effector CD4 T Cells in Active Tuberculosis Patients.Journal of immunology (Baltimore, Md. : 1950) · 2021Article
- Level of Pyrethroid-Resistance Associated with Cytochrome P450 Expression in German CockroachJournal of arthropod-borne diseases · 2021Article
- Reduced production of the major allergens Bla g 1 and Bla g 2 in Blattella germanica after antibiotic treatment.PloS one · 2021Article
- IgE and T Cell Reactivity to a Comprehensive Panel of Cockroach Allergens in Relation to Disease.Frontiers in immunology · 2020Article
- Development and Validation of aJournal of immunology research · 2020Article
- Article
Corrections and comments
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Authors and funding
16 authors at 8 institutions in 2 countries.
Funding
Abstract
German cockroach extract is used clinically to evaluate allergen-specific sensitization and for subcutaneous allergen-specific immunotherapy, though there are no guidelines for standardization in its manufacture. We performed an immunological evaluation of 12 different cockroach extracts prepared from different sources and their potency to induce allergen-specific T cell reactivity. PBMC from 13 cockroach allergic donors were expanded
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.