Evidence map›Paper›PMID 30891031›Full record

ReviewFrontiers in immunology2019

Metabolic Targets for Improvement of Allogeneic Hematopoietic Stem Cell Transplantation and Graft-vs.-Host Disease.

Natalia M Tijaro-Ovalle, Theodoros Karantanos, Hong-Tao Wang, Vassiliki A Boussiotis

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Immunometabolism of Liver Xenotransplantation and Prospective Solutions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. T-Cell Metabolism in GraftFrontiers in immunology · 2021
    Review
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Natalia M Tijaro-OvalleDivision of Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Theodoros KarantanosDivision of Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Hong-Tao WangDivision of Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Vassiliki A BoussiotisDivision of Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Beth Israel Deaconess Medical Center · US

Funding

Effects of PGE2 on Reconstitution of Hematopoiesis and Immunity after UCBTR01CA183605 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BOUSSIOTIS, VASSILIKI A, CUTLER, COREY S · 2013 to 2017
$3.8M
Advancing Treatment Outcomes in Malignant Glioma by Integrating Immunotherapy and Standard of Care using Genetically Engineered Mice that Recapitulate Molecular Feature of Human GliomaR01CA229784 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BOUSSIOTIS, VASSILIKI A, CHAREST, ALAIN · 2018 to 2022
$3.3M
Improving anti-tumor T cell immunity by targeting LDH-A functions beyond the Warburg effectR01CA212605 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BOUSSIOTIS, VASSILIKI A · 2017 to 2021
$2.8M
NCI NIH HHS R01 CA183605NCI NIH HHS R01 CA212605NCI NIH HHS R01 CA229784
6 · The paper itself

Abstract

Utilization of the adaptive immune system against malignancies, both by immune-based therapies to activate T cells

Indexed as

Hematopoietic Stem Cell TransplantationAnimalsGraft vs Host DiseaseHematopoietic Stem CellsHumansantigen presenting cells (APCs)GVHDGVLmetabolismT cells

Identifiers

PMID30891031
PMCPMC6411635
OpenAlexW2920125721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.