ArticleScientific reports2019
Temporal evolution of quantitative EEG within 3 days of birth in early preterm infants.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- The effects of betamethasone on the amplitude integrated EEG of infants born at 34- or 35-weeks gestation.Journal of perinatology : official journal of the California Perinatal Association · 2022Trial
- Applying a data-driven approach to quantify EEG maturational deviations in preterms with normal and abnormal neurodevelopmental outcomes.Scientific reports · 2020Trial
- Brain complexity in response to auditory stimulation improves evaluation of cerebral maturation in premature newborns.Pediatric research · 2026Article
- Pain, Opioids, and Functional Connectivity in Preterm Infants.Children (Basel, Switzerland) · 2026Article
- EEG Maturational Age Estimation: A Comparison of Visual and Automated Interpretation of the EEG in Preterm Infants.Journal of clinical medicine · 2025Article
- Article
- Early EEG-burst sharpness and 2-year disability in extremely preterm infants.Pediatric research · 2024Article
- Examining time-frequency mechanisms of full-fledged deep sleep development in newborns of different gestational age in the first days of their postnatal development.Scientific reports · 2022Article
- The relationship between interhemispheric synchrony, morphine and microstructural development of the corpus callosum in extremely preterm infants.Human brain mapping · 2022Article
- Early development of sleep and brain functional connectivity in term-born and preterm infants.Pediatric research · 2022Review
- Can EEG accurately predict 2-year neurodevelopmental outcome for preterm infants?Archives of disease in childhood. Fetal and neonatal edition · 2021Observational
- Early Diagnosis of Brain Injury in Premature Infants Based on Amplitude-Integrated EEG Scoring System.Journal of healthcare engineering · 2021Article
- Automated cot-side tracking of functional brain age in preterm infants.Annals of clinical and translational neurology · 2020Article
- Measuring Cot-Side the Effects of Parenteral Nutrition on Preterm Cortical Function.Frontiers in human neuroscience · 2020Article
- Quantitative Preterm EEG Analysis: The Need for Caution in Using Modern Data Science Techniques.Frontiers in pediatrics · 2019Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For the premature newborn, little is known about changes in brain activity during transition to extra-uterine life. We aim to quantify these changes in relation to the longer-term maturation of the developing brain. We analysed EEG for up to 72 hours after birth from 28 infants born <32 weeks of gestation. These infants had favourable neurodevelopment at 2 years of age and were without significant neurological compromise at time of EEG monitoring. Quantitative EEG was generated using features representing EEG power, discontinuity, spectral distribution, and inter-hemispheric connectivity. We found rapid changes in cortical activity over the 3 days distinct from slower changes associated with gestational age: for many features, evolution over 1 day after birth is equivalent to approximately 1 to 2.5 weeks of maturation. Considerable changes in the EEG immediately after birth implies that postnatal adaption significantly influences cerebral activity for early preterm infants. Postnatal age, in addition to gestational age, should be considered when analysing preterm EEG within the first few days after birth.
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