Evidence map›Paper›PMID 30890614›Full record

ArticlemBio2019

Staphylococcal Superantigens Stimulate Epithelial Cells through CD40 To Produce Chemokines.

Patrick M Schlievert, Michael P Cahill, Bruce S Hostager, Amanda J Brosnahan, Aloysius J Klingelhutz, Francoise A Gourronc, Gail A Bishop, Donald Y M Leung

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
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  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Microbiology spectrum · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Type 2 Inflammation Contributes to Skin Barrier Dysfunction in Atopic Dermatitis.JID innovations : skin science from molecules to population health · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Patrick M SchlievertDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA patrick-schlievert@uiowa.edu.
Michael P CahillDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Bruce S HostagerDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Amanda J BrosnahanDepartment of Microbiology and Immunology, School of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Aloysius J KlingelhutzDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Francoise A GourroncDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Gail A BishopDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Donald Y M LeungDepartment of Pediatrics, National Jewish Health, Denver, Colorado, USA.
University of Iowa · USUniversity of Colorado Denver · USUniversity of Minnesota · US

Funding

Targeted Microbiome Transplant in Atopic DermatitisU19AI117673 · NIAID · NATIONAL JEWISH HEALTH · PI GALLO, RICHARD L · 2015 to 2019
$30.6M
Flow Cytometry Cell SorterS10OD016199 · OD · UNIVERSITY OF IOWA · PI BALLAS, ZUHAIR K. · 2015 to 2015
$443k
NIAID NIH HHS U19 AI117673NIH HHS S10 OD016199
6 · The paper itself

Abstract

Mucosal and skin tissues form barriers to infection by most bacterial pathogens.

Indexed as

Bacterial ToxinsCD40 AntigensCells, CulturedChemokinesEnterotoxinsEpithelial CellsGene Knockout TechniquesHumansStaphylococcus aureusSuperantigensBacterial ToxinsCD40 AntigensChemokinesenterotoxin B, staphylococcalenterotoxin C, staphylococcalenterotoxin F, StaphylococcalEnterotoxinsSuperantigensCD40chemokinesStaphylococcus aureussuperantigenstoxic shock syndrome toxin

Identifiers

PMID30890614
PMCPMC6426597
OpenAlexW2921620695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.