Evidence map›Paper›PMID 30890562›Full record

ArticleJournal of lipid research2019

AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin.

Mario Ruiz, Marcus Ståhlman, Jan Borén, Marc Pilon

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 73 citations in OpenAlex.

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  14. Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function.Cold Spring Harbor perspectives in biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mario RuizDepartment of Chemistry and Molecular Biology; University of Gothenburg, Gothenburg, Sweden.
Marcus StåhlmanDepartment of Molecular and Clinical Medicine/Wallenberg Laboratory Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Jan BorénDepartment of Molecular and Clinical Medicine/Wallenberg Laboratory Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Marc PilonDepartment of Chemistry and Molecular Biology; University of Gothenburg, Gothenburg, Sweden. Electronic address: marc.pilon@cmb.gu.se.
University of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The FA composition of phospholipids must be tightly regulated to maintain optimal cell membrane properties and compensate for a highly variable supply of dietary FAs. Previous studies have shown that AdipoR2 and its homologue PAQR-2 are important regulators of phospholipid FA composition in HEK293 cells and

Indexed as

Membrane FluidityAdiponectinCells, CulturedHEK293 CellsHep G2 CellsHomeostasisHumansReceptors, AdiponectinAdiponectinADIPOR1 protein, humanADIPOR2 protein, humanReceptors, Adiponectindesaturasesfatty acidslipotoxicitymetabolismpalmitatephospholipidsplasma membranereceptors

Identifiers

PMID30890562
PMCPMC6495173
OpenAlexW2924688481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.