Evidence map›Paper›PMID 30890555›Full record

ArticleThe Journal of experimental medicine2019

Dual roles of

Radek C Skoda, Juerg Schwaller

Registry-linked trialOpen access · bronzeAbstract readComment
In one paragraph

Article in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04215822 (PHF19 Gene Expression and EZH2 Gene Deletion as Potential Biomarkers of Acute Myeloid Leukemia), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04215822 unknown statusnot on this mapstarted 2020, after this paper: background citation

PHF19 Gene Expression and EZH2 Gene Deletion as Potential Biomarkers of Acute Myeloid Leukemia

Typeobservational_patient_registrySponsorAssiut UniversityRan2020 to 2022Enrolled80ConditionsAcute Myeloid LeukemiaArmsCytogenetic analysis (FISH) for EZH2 gene deletion. -Real time PCR for PHF 19 gene expression.
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Aberrant Expression ofBioMed research international · 2019
    Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Cells · 2022
    Review
  9. Article
  10. Epigenetics of Aging and Aging-Associated Diseases.International journal of molecular sciences · 2021
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Radek C SkodaDepartment of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland radek.skoda@unibas.ch.
Juerg SchwallerDepartment of Biomedicine, University Children's Hospital Basel and University of Basel, Basel, Switzerland.
University of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of

Indexed as

Leukemia, Myeloid, AcuteCarcinogenesisEnhancer of Zeste Homolog 2 ProteinHumansEnhancer of Zeste Homolog 2 ProteinEZH2 protein, human

Identifiers

PMID30890555
PMCPMC6446873
OpenAlexW2925034404

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.