Evidence map›Paper›PMID 30890469›Full record

ArticleBiochimica et biophysica acta. Biomembranes2019

Mercury leads to abnormal red blood cell adhesion to laminin mediated by membrane sulfatides.

Birnur Akkaya, Erdem Kucukal, Jane A Little, Umut A Gurkan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochimica et biophysica acta. Biomembranes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Birnur AkkayaScience Faculty, Department of Molecular Biology and Genetics Department, Cumhuriyet University, Sivas, Turkey; Case Biomanufacturing and Microfabrication Laboratory, Mechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, OH, USA.
Erdem KucukalCase Biomanufacturing and Microfabrication Laboratory, Mechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, OH, USA.
Jane A LittleDepartment of Hematology and Oncology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Umut A GurkanCase Biomanufacturing and Microfabrication Laboratory, Mechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, OH, USA; Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, USA; Department of Orthopaedics, Case Western Reserve University, Cleveland, OH, USA. Electronic address: umut@case.edu.
Case Western Reserve University · USUniversity Hospitals of Cleveland · US

Funding

Standardized Monitoring of Cellular Adhesion to Improve Clinical Care in Sickle Cell DiseaseR01HL133574 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI GURKAN, UMUT A., LITTLE, JANE · 2016 to 2020
$2.0M
NHLBI NIH HHS R01 HL133574
6 · The paper itself

Abstract

Exposure to mercury is associated with numerous health problems, affecting different parts of the human body, including the nervous and cardiovascular systems in adults and children; however, the underlying mechanisms are yet to be fully elucidated. We investigated the role of membrane sulfatide on mercuric ion (Hg

Indexed as

Cell AdhesionDose-Response Relationship, DrugErythrocytes, AbnormalHumansLamininMercuric ChlorideLamininMercuric ChlorideAdhesion to lamininErythrocyteMercuryMercury exposureRed blood cellSulfatides

Identifiers

PMID30890469
PMCPMC7098422
OpenAlexW2922484686

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.