Evidence map›Paper›PMID 30889933›Full record

ArticleGenes2019

Identification of Zebrafish Calcium Toolkit Genes and their Expression in the Brain.

Iga Wasilewska, Rishikesh Kumar Gupta, Oksana Palchevska, Jacek Kuźnicki

Abstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. 6-Gingerol, a Major Constituent ofInternational journal of molecular sciences · 2021
    Article
  6. Knockout ofInternational journal of molecular sciences · 2020
    Article
  7. Cells · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iga WasilewskaInternational Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland. iwasilewska@iimcb.gov.pl.
Rishikesh Kumar GuptaInternational Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland. rkgupta@iimcb.gov.pl.
Oksana PalchevskaInternational Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland. opalchevska@iimcb.gov.pl.
Jacek KuźnickiInternational Institute of Molecular and Cell Biology in Warsaw, Trojdena 4, 02-109 Warsaw, Poland. jacek.kuznicki@iimcb.gov.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zebrafish are well-suited for in vivo calcium imaging because of the transparency of their larvae and the ability to express calcium probes in various cell subtypes. This model organism has been used extensively to study brain development, neuronal function, and network activity. However, only a few studies have investigated calcium homeostasis and signaling in zebrafish neurons, and little is known about the proteins that are involved in these processes. Using bioinformatics analysis and available databases, the present study identified 491 genes of the zebrafish Calcium Toolkit (CaTK). Using RNA-sequencing, we then evaluated the expression of these genes in the adult zebrafish brain and found 380 hits that belonged to the CaTK. Based on quantitative real-time polymerase chain reaction arrays, we estimated the relative mRNA levels in the brain of CaTK genes at two developmental stages. In both 5 dpf larvae and adult zebrafish, the highest relative expression was observed for

Indexed as

Calcium SignalingAnimalsBrainGene Expression ProfilingGene Expression Regulation, DevelopmentalModels, AnimalSequence Analysis, RNAZebrafishZebrafish ProteinsZebrafish Proteinsbioinformaticsbraincalcium homeostasiscalcium signalingcalcium toolkitgene ontologyneuronsRNA-sequencingRT-PCRzebrafish

Identifiers

PMID30889933
PMCPMC6471419

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.