Evidence map›Paper›PMID 30889909›Full record

ArticleBiomolecules2019

Diagnostic Value of Soluble Urokinase-Type Plasminogen Activator Receptor in Addition to High-Sensitivity Troponin I in Early Diagnosis of Acute Myocardial Infarction.

Nils A Sörensen, Günay Dönmez, Johannes T Neumann, Julius Nikorowitsch, Nicole Rübsamen, Stefan Blankenberg, Dirk Westermann, Tanja Zeller, Mahir Karakas

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Nils A SörensenDepartment of General and Interventional Cardiology, University Heart Center, 20246 Hamburg, Germany. n.soerensen@uke.de.
Günay DönmezDepartment of General and Interventional Cardiology, University Heart Center, 20246 Hamburg, Germany. guenay.doenmez@gmx.de.
Johannes T NeumannDepartment of General and Interventional Cardiology, University Heart Center, 20246 Hamburg, Germany. j.neumann@uke.de.
Julius NikorowitschDepartment of General and Interventional Cardiology, University Heart Center, 20246 Hamburg, Germany. j.nikorowitsch@uke.de.
Nicole RübsamenDepartment of General and Interventional Cardiology, University Heart Center, 20246 Hamburg, Germany. n.ruebsamen@uke.de.
Stefan BlankenbergDepartment of General and Interventional Cardiology, University Heart Center, 20246 Hamburg, Germany. s.blankenberg@uke.de.
Dirk WestermannDepartment of General and Interventional Cardiology, University Heart Center, 20246 Hamburg, Germany. d.westermann@uke.de.
Tanja ZellerDepartment of General and Interventional Cardiology, University Heart Center, 20246 Hamburg, Germany. t.zeller@uke.de.
Mahir KarakasDepartment of General and Interventional Cardiology, University Heart Center, 20246 Hamburg, Germany. m.karakas@uke.de.
Universität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The soluble urokinase-type plasminogen activator receptor (suPAR) is a new marker for immune activation and inflammation and may provide diagnostic value on top of established biomarkers in patients with suspected acute myocardial infarction (AMI). Here, we evaluate the diagnostic potential of suPAR levels on top of high-sensitivity troponin I (hs-TnI) in a cohort of patients with suspected AMI. A total of 1220 patients presenting to the emergency department with suspected AMI were included, of whom 245 were diagnosed with AMI. Median suPAR levels at admission were elevated in subjects with AMI compared to non-AMI (3.8 ng/mL vs 3.3 ng/mL,

Indexed as

Acute DiseaseAgedBiomarkersEarly DiagnosisFemaleHumansMaleMiddle AgedMyocardial InfarctionReceptors, Urokinase Plasminogen ActivatorSolubilityTroponin IBiomarkersReceptors, Urokinase Plasminogen ActivatorTroponin Iacute coronary syndromediagnosissuPARtroponin

Identifiers

PMID30889909
PMCPMC6468350
OpenAlexW2920825551

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.