Evidence map›Paper›PMID 30889882›Full record

ArticleMarine drugs2019

Dietary Supplementation with Low-Molecular-Weight Fucoidan Enhances Innate and Adaptive Immune Responses and Protects against

Pai-An Hwang, Hong-Ting Victor Lin, Hsin-Yuan Lin, Szu-Kuan Lo

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Fucoidan Improves Tumour Control and Liver Function in TACE for Unresectable Hepatocellular Carcinoma: A Randomised Trial.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Trial
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Study on Immunoregulatory Effects of Fucoidan fromMolecules (Basel, Switzerland) · 2023
    Article
  12. Review
  13. Article
  14. Immune-Enhancing Effect ofMolecules (Basel, Switzerland) · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Effects of Fucoidan Isolated FromFrontiers in immunology · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pai-An HwangDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, No. 2, Beining Road, Keelung 20246, Taiwan. amperehwang@gmail.com.
Hong-Ting Victor LinDepartment of Food Science, National Taiwan Ocean University, Keelung 20246, Taiwan. HL358@ntou.edu.tw.ORCID 0000-0002-8737-208X
Hsin-Yuan LinDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, No. 2, Beining Road, Keelung 20246, Taiwan. 2063B003@mail.ntou.edu.tw.
Szu-Kuan LoGi-Kang Clinic, No. 155, Yanping Rd., Zhongli Dist., Taoyuan 32043, Taiwan. a912164@yahoo.com.tw.
National Taiwan Ocean University · TW

Funding

Ministry of Science and Technology, Taiwan 107-2320-B-019-001-MY2The Center of Excellence for the Oceans of National Taiwan Ocean University NTOU-RD-AA-2016-1-02012
6 · The paper itself

Abstract

In this study, the low-molecular-weight (LMW) fucoidan, rich in fucose and sulfate, was extracted and purified from the edible brown seaweed,

Indexed as

Dietary SupplementsAdaptive ImmunityAnimalsAntigens, BacterialCells, CulturedDisease Models, AnimalFemaleHumansImmunity, InnateLaminariaMiceMice, Inbred BALB CMolecular WeightMycoplasma pneumoniaePneumonia, MycoplasmaPolysaccharidesAntigens, BacterialfucoidanPolysaccharidesProtective Agentsadjuvantantigen-specific antibodylow molecular weight fucoidanMycoplasma pneumoniaeNK cell

Identifiers

PMID30889882
PMCPMC6471482
OpenAlexW2921309174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.