Evidence map›Paper›PMID 30889783›Full record

ArticleInternational journal of molecular sciences2019

Fatty Acid Synthesis and Degradation Interplay to Regulate the Oxidative Stress in Cancer Cells.

Valeryia Mikalayeva, Ieva Ceslevičienė, Ieva Sarapinienė, Vaidotas Žvikas, Vytenis Arvydas Skeberdis, Valdas Jakštas, Sergio Bordel

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Small molecule inhibitors for cancer metabolism: promising prospects to be explored.Journal of cancer research and clinical oncology · 2023
    Review
  9. Article
  10. Oxidative Stress and Inflammation in B-Cell Lymphomas.Antioxidants (Basel, Switzerland) · 2023
    Review
  11. Review
  12. Article
  13. Adiponectin triggers breast cancer cell death via fatty acid metabolic reprogramming.Journal of experimental & clinical cancer research : CR · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Valeryia MikalayevaInstitute of Cardiology, Lithuanian University of Health Sciences, LT 44307 Kaunas, Lithuania. Valeryia.Mikalayeva@lsmuni.lt.
Ieva CeslevičienėInstitute of Cardiology, Lithuanian University of Health Sciences, LT 44307 Kaunas, Lithuania. Ieva.Cesleviciene@lsmuni.lt.
Ieva SarapinienėInstitute of Cardiology, Lithuanian University of Health Sciences, LT 44307 Kaunas, Lithuania. Ieva.Sarapiniene@lsmuni.lt.
Vaidotas ŽvikasInstitute of Pharmaceutical Technologies, Lithuanian University of Health Sciences, LT 44307 Kaunas, Lithuania. Vaidotas.Zvikas@lsmuni.lt.
Vytenis Arvydas SkeberdisInstitute of Cardiology, Lithuanian University of Health Sciences, LT 44307 Kaunas, Lithuania. Arvydas.Skeberdis@lsmuni.lt.
Valdas JakštasInstitute of Pharmaceutical Technologies, Lithuanian University of Health Sciences, LT 44307 Kaunas, Lithuania. Valdas.Jakstas@lsmuni.lt.
Sergio BordelInstitute of Cardiology, Lithuanian University of Health Sciences, LT 44307 Kaunas, Lithuania. Sergio.Bordel@lsmuni.lt.
Lithuanian University of Health Sciences · LT

Funding

Lietuvos Mokslo Taryba SEN-04/2016
6 · The paper itself

Abstract

Both cytosolic fatty acid synthesis (FAS) and mitochondrial fatty acid oxidation (FAO) have been shown to play a role in the survival and proliferation of cancer cells. This study aimed to confirm experimentally whether FAS and FAO coexist in breast cancer cells (BCC). By feeding cells with

Indexed as

Oxidative StressBreast NeoplasmsCarbon IsotopesCell Line, TumorFatty AcidsFatty Acid SynthasesFemaleHumansMembrane Potential, MitochondrialMetabolic Flux AnalysisOxidation-ReductionCarbon IsotopesFatty AcidsFatty Acid Synthasescancerlipidsmetabolic flux analysismetabolismoxidative stress

Identifiers

PMID30889783
PMCPMC6471536
OpenAlexW2921877300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.