Evidence map›Paper›PMID 30889512›Full record

ReviewCell calcium2019

Redox regulation of ER and mitochondrial Ca

Suresh K Joseph, David M Booth, Michael P Young, György Hajnóczky

Abstract readReview
In one paragraph

Review in Cell calcium, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Molecular mechanisms attributed to colistin renal proximal tubular epithelial cytotoxicity.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Emerging mitochondrial signaling mechanisms in cardio-oncology: beyond oxidative stress.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  16. Reticulocalbin3: A CaCancer science · 2022
    Article
  17. Balancing ER-Mitochondrial CaTrends in cell biology · 2021
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suresh K JosephMitoCare, Department of Pathology and Cell Biology, Thomas Jefferson University, Philadelphia, PA, 19107, USA. Electronic address: Suresh.joseph@jefferson.edu.
David M BoothMitoCare, Department of Pathology and Cell Biology, Thomas Jefferson University, Philadelphia, PA, 19107, USA.
Michael P YoungMitoCare, Department of Pathology and Cell Biology, Thomas Jefferson University, Philadelphia, PA, 19107, USA.
György HajnóczkyMitoCare, Department of Pathology and Cell Biology, Thomas Jefferson University, Philadelphia, PA, 19107, USA.

Funding

Redox Regulation of Intracellular Calcium SignalingR01DK103558 · NIDDK · THOMAS JEFFERSON UNIVERSITY · PI HAJNOCZKY, GYORGY, JOSEPH, SURESH K · 2015 to 2018
$1.4M
Regulation of inositol trisphosphate receptorsR01GM132611 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI JOSEPH, SURESH K · 2020 to 2023
$1.3M
NIDDK NIH HHS R01 DK103558NIGMS NIH HHS R01 GM132611
6 · The paper itself

Abstract

Physiological signaling by reactive oxygen species (ROS) and their pathophysiological role in cell death are well recognized. This review focuses on two ROS targets that are key to local Ca

Indexed as

Calcium SignalingAnimalsCalciumCell DeathCell SurvivalEndoplasmic ReticulumHumansMitochondriaOxidation-ReductionCalciumCa(2+)IP(3)IP(3) receptorMitochondrial calcium uniporterReactive oxygen speciesRedox regulation

Identifiers

PMID30889512
PMCPMC8409742

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.