Evidence map›Paper›PMID 30888975›Full record

ArticleCoronary artery disease2019

Pulse pressure correlates with coronary artery calcification and risk for coronary heart disease: a study of elderly individuals in the rural region of Southwest China.

Xinhua Wu, Yong-Jian Geng, Zhangrong Chen, Mayil S Krishnam, Robert Detrano, Hong Liu, Wei Yang, Tianzhao Ouyang, Yu Dong, Ying Yang and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Coronary artery disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Xinhua WuDepartment of Cardiology, The First Affiliated Hospital of Dali University, Dali, China.
Yong-Jian GengCenter for Cardiovascular Biology and Atherosclerosis, McGovern School of Medicine, University of Texas Health Science Center at Houston, Houston, Texas.
Zhangrong ChenDepartment of Cardiology, The First Affiliated Hospital of Dali University, Dali, China.
Mayil S KrishnamDepartment of Radiological Sciences, University of California Irvine, Irvine, California, USA.
Robert DetranoDepartment of Radiological Sciences, University of California Irvine, Irvine, California, USA.
Hong LiuDepartment of Cardiology, The First Affiliated Hospital of Dali University, Dali, China.
Wei YangDepartment of Cardiology, The First Affiliated Hospital of Dali University, Dali, China.
Tianzhao OuyangDepartment of Cardiology, The First Affiliated Hospital of Dali University, Dali, China.
Yu DongDepartment of Cardiology, The First Affiliated Hospital of Dali University, Dali, China.
Ying YangDepartment of Cardiology, The First Affiliated Hospital of Dali University, Dali, China.
Shiquan KuangDepartment of Cardiology, The First Affiliated Hospital of Dali University, Dali, China.
Dali University · CNUniversity of California, Irvine · USThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study aimed to define the relationship between pulse pressure (PP) and coronary artery calcification (CAC), a proven surrogate marker for coronary heart disease. PATIENTS AND

methodsA total of 170 participants 50-70 years of age from 11 villages of Yunnan Province of China were enrolled randomly into this study. They were examined routinely for diastolic and systolic blood pressure, PP, and CAC.

resultsThe average PP in the CAC-positive group was significantly higher than that in the CAC-negative group. In the positive CAC group, there were significantly positive correlations between PP and CAC score, volume, mass, as well as density. The area under the receiver operating characteristic curve analysis showed that PP performed well in predicting CAC.

conclusionIn conclusion, among the rural people of southwest of China, PP correlates positively with the coronary calcium Agatston score, volume, mass, and density. PP predicted CAC as well as Framingham Risk Score. The measurement of PP widening may serve as an alternative and convenient method for assessing CAC risk in rural populations with poor accessibility and economic disadvantage over coronary computed tomography scanning.

Indexed as

Blood PressureRural HealthAgedChinaComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseFemaleHumansMaleMiddle AgedRisk AssessmentRisk FactorsVascular Calcification

Identifiers

PMID30888975
PMCPMC6504121
OpenAlexW2923269374

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.