ArticleJournal of medicinal food2019
Determination of Total Chlorogenic Acids in Commercial Green Coffee Extracts.
Article in Journal of medicinal food, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- From Conventional Methods to Innovation: Caffeine and Chlorogenic Acid Extraction and Quantification in the Rise of Smart and Green Techniques-A Systematic Review.Molecules (Basel, Switzerland) · 2026Pooled it
- Polyphenol profiling and multi-target antioxidant, anti-inflammatory and antidiabetic activity of Sorbus commixta Hedl. leaves.Scientific reports · 2026Article
- A New Segmented Gradient HPLC-DAD and Spectra Index Plots for Measuring Caffeine and Chlorogenic Acid in Dark and Green Coffees.ACS omega · 2025Article
- Chlorogenic acid induces apoptosis and cell-cycle arrest in colorectal cancer cells.Molecular biology reports · 2023Article
- Article
- Use of Coffee Bean Bagasse Extracts in the Brewing of Craft Beers: Optimization and Antioxidant Capacity.Molecules (Basel, Switzerland) · 2022Article
- Potential Antimicrobial Properties of Coffee Beans and Coffee By-Products Against Drug-ResistantFrontiers in nutrition · 2022Article
- Rapid and simultaneous determination of trigonelline, caffeine, and chlorogenic acid in green coffee bean extract.Food science & nutrition · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity and type II diabetes are serious health problems and are among the leading causes of death. There are a few prescription weight loss drugs, but they have a high cost and their adverse effects have limited their widespread use. For the consumer, the use of dietary supplements represents a natural and presumably safer means of losing weight. A high-pressure liquid chromatography (HPLC) method was developed to provide a simple, inexpensive method for analysis of 54 commercially available extracts of green coffee beans. Both chlorogenic acids (CGAs), which are the purported bioactives, and caffeine were measured using 5-chloroquinic acid as the standard and published extinction coefficients for the other monomeric and dimeric CGAs present. The average labeled dose of CGA was 233 mg, whereas the average calculated by HPLC analysis was only 157 mg. Thus, the consumer is likely to obtain product containing a little more than half of the reported label amount of CGA. Caffeine levels ranged from 0% to 17%. The marketing literature touts 50% CGA content as being the gold standard of green coffee bean extract products. Based on this value, only 28% of the commercial products we studied met this goal.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.