ArticleAmerican journal of respiratory and critical care medicine2019
Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma.
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In one paragraph
Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
173citing papers in PubMed, 1 pooled it
10.2field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
173 citing papers in PubMed, 1 synthesis or guideline pooled it, 260 citations in OpenAlex.
- Characteristics and Role of Neutrophil Extracellular Traps in Asthma.Inflammation · 2022Pooled it
- Necrostatin-1 Ameliorates Neutrophilic Inflammation in Asthma by Suppressing MLKL Phosphorylation to Inhibiting NETs Release.Frontiers in immunology · 2020Trial
- Article
- Type 2-low Asthma: Epidemiology, Multiomics, and Emerging Therapies.Current allergy and asthma reports · 2026Review
- Cynaroside reduces neutrophil extracellular trap formation and disease severity in a mouse model of asthma by inhibiting the COX-2/TNF-alpha/NF-kB axis.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Beyond Infection-Indoor Airborne Pathogens as Contributors to Respiratory Inflammation and Immune Dysregulation: A Narrative Review.Pathogens (Basel, Switzerland) · 2026Review
- Multicellular crosstalk in neutrophilic asthma: unraveling the pathogenic web of steroid resistance and emerging precision therapies.Journal of translational medicine · 2026Review
- Review
- Integration of bioinformatics analysis and experimental verification reveals the role of neutrophil extracellular traps in silica nanoparticles-induced lung injury.Journal of nanobiotechnology · 2026Article
- Targeting neutrophil extracellular traps (NETs): a promising immunotherapeutic approach for pulmonary diseases.Molecular biology reports · 2026Review
- Asthma endotypes and theratypes.Chinese medical journal pulmonary and critical care medicine · 2026Review
- Neutrophil extracellular traps induce airway epithelial-mesenchymal transition in a neutrophil-dominant asthmatic murine model through Hedgehog/Gli1 pathway.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
- The context-dependent role of group 2 innate lymphoid cells in lung diseases.Acta biochimica et biophysica Sinica · 2026Review
- Beyond the Usual Suspects: Unmasking Low-T2 Asthma in Children.Journal of clinical medicine · 2026Review
- Neutrophil degranulation in the lung microenvironment linked to idiopathic pulmonary fibrosis severity and survival.iScience · 2026Article
- Itaconate Modulates Neutrophil Homeostasis to Ameliorate Airway Inflammation in Diesel Exhaust Particles-exacerbated Asthma via Inhibiting NETs Formation.International journal of biological sciences · 2026Article
- Mitochondrial reprogramming of neutrophil extracellular traps in chronic obstructive pulmonary disease and asthma: toward a phenotype-driven therapeutic framework.Frontiers in immunology · 2026Review
- Neutrophil to High-Density Lipoprotein Cholesterol Ratio and All-Cause Mortality Among Asthmatic Individuals: A Cohort Study.Mediators of inflammation · 2026Article
- Targeting neutrophil extracellular traps: an emerging strategy for improving the management of refractory asthma.Frontiers in medicine · 2026Article
- Language-dependent variation in observed mechanistic performance of web-enabled large language models across myeloid-mucosal immune contexts: a blinded expert evaluation.Frontiers in immunology · 2026Article
113 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
24 authors at 10 institutions in 2 countries.
Marrah E Lachowicz-Scroggins1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.ORCID 0000-0002-3173-5662
Eleanor M Dunican3 School of Medicine and St. Vincent's University Hospital, University College Dublin, Dublin, Ireland.ORCID 0000-0003-4014-5100
Annabelle R Charbit1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.
Wilfred Raymond1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.
Mark R Looney1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.
Michael C Peters1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.
Erin D Gordon1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.
Prescott G Woodruff1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.
Emma Lefrançais1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.
Brenda R Phillips4 Division of Statistics and Bioinformatics, Department of Public Health Sciences, Pennsylvania State University, Hershey, Pennsylvania.
David T Mauger4 Division of Statistics and Bioinformatics, Department of Public Health Sciences, Pennsylvania State University, Hershey, Pennsylvania.
Suzy A Comhair5 Department of Pathobiology, Cleveland Clinic, Cleveland, Ohio.
Serpil C Erzurum5 Department of Pathobiology, Cleveland Clinic, Cleveland, Ohio.
Mats W Johansson6 Department of Biomolecular Chemistry and.
Nizar N Jarjour7 Section of Pulmonary and Critical Care Medicine, University of Wisconsin School of Medicine, Madison, Wisconsin.
Andrea M Coverstone8 Division of Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.
Mario Castro8 Division of Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.
Annette T Hastie9 Pulmonary Section, Department of Internal Medicine, School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
Eugene R Bleecker10 Division of Genetics, Genomics, and Precision Medicine, Department of Medicine, University of Arizona, Tucson, Arizona.
Merritt L Fajt11 Pulmonary, Allergy and Critical Care Medicine Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;and.
Sally E Wenzel11 Pulmonary, Allergy and Critical Care Medicine Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;and.
Elliot Israel12 Division of Pulmonary and Critical Care Medicine, Brigham Research Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Bruce D Levy12 Division of Pulmonary and Critical Care Medicine, Brigham Research Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
John V Fahy1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, and.
University of California, San Francisco · USBrigham and Women's Hospital · USCleveland Clinic · USPennsylvania State University · USUniversity of Pittsburgh · USWashington University in St. Louis · USUniversity College Dublin · IEUniversity of Arizona · USUniversity of Wisconsin–Madison · USWake Forest University · US
Funding
Understanding Asthma EndotypesU19AI077439 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PRESCOTT G WOODRUFF · 2008 to 2026
$41.1MRole of miRNAs in Th2-Driven inflammation in AsthmaP01HL107202 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LOCKSLEY, RICHARD M · 2012 to 2023
$23.3MPEDIATRIC ASTHMA NETWORK DATA COORDINATING CENTERU10HL064313 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 1999 to 2008
$18.3MClinical Coordinating Center for the Severe Asthma Research Program (SARP)U10HL109086 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 2011 to 2017
$8.1MSpecialized Pro-Resolving Mediators in AsthmaR01HL122531 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LEVY, BRUCE D · 2014 to 2024
$4.7MClinical and Molecular Phenotypes of Severe AsthmaU10HL109146 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FAHY, JOHN V · 2011 to 2016
$4.0MUnderstanding the Molecular Genetic Mechanisms of Asthma Risk Loci: IL33, IL1RL1, and GSDMB - COVID 19 SupplementR01AI136962 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORDON, ERIN D. · 2018 to 2022
$3.4MFine-tuning the Neutrophilic Response to PneumoniaR01AI125445 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LOONEY, MARK ROBERTS · 2016 to 2020
$2.2MMentoring Research in Precision Medicine for Lung DiseaseK24HL137013 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PRESCOTT G WOODRUFF · 2017 to 2026
$1.2MNHLBI NIH HHS K24 HL137013NHLBI NIH HHS P01 HL107202NHLBI NIH HHS R01 HL122531NHLBI NIH HHS U10 HL064313NHLBI NIH HHS U10 HL109086NHLBI NIH HHS U10 HL109146NIAID NIH HHS R01 AI125445NIAID NIH HHS R01 AI136962NIAID NIH HHS U19 AI077439
Abstract
PubMed holds no abstract for this paper.
Indexed as
Acute DiseaseAdultAsthmaBlotting, WesternCase-Control StudiesDNAExtracellular TrapsFemaleGlucosephosphate DehydrogenaseHumansInflammasomesInterleukin-6Interleukin-8Longitudinal StudiesMaleMiddle AgedDNAGlucosephosphate DehydrogenaseInflammasomesInterleukin-6Interleukin-8asthmacaspase 1extracellular DNAIL-1βneutrophil extracellular traps
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What OpenQuestion holds
Textmetadata
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.