Evidence map›Paper›PMID 30888573›Full record

ArticleAIDS and behavior2019

Measuring Antiretroviral Adherence Among Young People Living with HIV: Observations from a Real-Time Monitoring Device Versus Self-report.

Lacey Craker, Nicholas Tarantino, Laura Whiteley, Larry Brown

Abstract read
In one paragraph

Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  6. Innovative Approaches to Enhance and Measure Medication Adherence in Chronic Disease Management: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lacey CrakerBradley/Hasboro Children's Research Center, 167 Point Street, Suite 161, Providence, RI, 02903, USA.
Nicholas TarantinoBradley/Hasboro Children's Research Center, 167 Point Street, Suite 161, Providence, RI, 02903, USA.
Laura WhiteleyDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Larry BrownBradley/Hasboro Children's Research Center, 167 Point Street, Suite 161, Providence, RI, 02903, USA. lkbrown@lifespan.org.

Funding

Training in Child/Adolescent Biobehavioral HIV ResearchT32MH078788 · NIMH · RHODE ISLAND HOSPITAL · PI LARRY K BROWN · 2007 to 2026
$6.2M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
A Pilot Gaming Adherence Program for Youth Living with HIVR01HD074846 · NICHD · RHODE ISLAND HOSPITAL · PI BROWN, LARRY K · 2012 to 2014
$1.5M
NICHD NIH HHS R01 HD074846NIMH NIH HHS R25 MH083620NIMH NIH HHS T32 MH078788NIMH NIH HHS T32MH078788
6 · The paper itself

Abstract

This report compares self-report (SR) antiretroviral (ARV) adherence data to adherence data collected via Wisepill, a real-time electronic monitoring (EM) device, among young people living with HIV (YPLH) in the southern United States. Participants (n = 66; ages 16 to 26) were followed for 14 weeks. Descriptive analyses were used to compare SR to EM data. Correlations and a linear regression were conducted to explore factors possibly associated with SR-EM discrepancies. We also examined associations between various levels of SR and EM adherence and viral suppression/non-suppression at 14 weeks. Rates of SR adherence were maintained between 87% and 92% while rates of EM adherence declined from 64% to 34%. YPLH who were ARV-experienced, had lower treatment motivation, and reported more frequent recent marijuana use, had a greater discrepancy between their SR and EM adherence levels compared to other YPLH. Higher rates of SR and EM adherence were independently associated with a decline in viral load. A sensitivity analysis also revealed that SR adherence was a better predictor of viral non-suppression, whereas EM adherence was a better predictor of viral suppression. These measurement approaches are discussed in the context of providing clinical care to YPLH.

Indexed as

Antiretroviral Therapy, Highly ActiveDrug MonitoringAdolescentAdultAnti-Retroviral AgentsFemaleHealth Knowledge, Attitudes, PracticeHIVHIV InfectionsHumansMaleMedication AdherenceSelf DisclosureSelf ReportViral LoadYoung AdultAnti-Retroviral AgentsAdherenceAntiretroviralHIVMeasurementYouth

Identifiers

PMID30888573
PMCPMC6650304

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.