Evidence map›Paper›PMID 30888570›Full record

ArticleJapanese journal of radiology2019

Distinction between benign and malignant breast masses at breast ultrasound using deep learning method with convolutional neural network.

Tomoyuki Fujioka, Kazunori Kubota, Mio Mori, Yuka Kikuchi, Leona Katsuta, Mai Kasahara, Goshi Oda, Toshiyuki Ishiba, Tsuyoshi Nakagawa, Ukihide Tateishi

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In one paragraph

Article in Japanese journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it, 177 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The Evolution and Clinical Impact of Deep Learning Technologies in Breast MRI.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Review
  6. Article
  7. Whole-lesion-aware network based on freehand ultrasound video for breast cancer assessment: a prospective multicenter study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  8. Article
  9. Article
  10. Breast Cancer Detection on Dual-View Sonography via Data-Centric Deep Learning.IEEE open journal of engineering in medicine and biology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Research on ultrasound-based radiomics: a bibliometric analysis.Quantitative imaging in medicine and surgery · 2024
    Article
  18. Article
  19. Article
  20. Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Tomoyuki FujiokaDepartment of Radiology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.ORCID http://orcid.org/0000-0002-7141-8901
Kazunori KubotaDepartment of Radiology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Mio MoriDepartment of Radiology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan. m_mori_116@yahoo.co.jp.ORCID http://orcid.org/0000-0002-6107-4519
Yuka KikuchiDepartment of Radiology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Leona KatsutaDepartment of Radiology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Mai KasaharaDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Goshi OdaDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Toshiyuki IshibaDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Tsuyoshi NakagawaDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Ukihide TateishiDepartment of Radiology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Tokyo Medical and Dental University · JP

Funding

KAKENHI-PROJECT 16K10270
6 · The paper itself

Abstract

purposeWe aimed to use deep learning with convolutional neural network (CNN) to discriminate between benign and malignant breast mass images from ultrasound. MATERIALS AND

methodsWe retrospectively gathered 480 images of 96 benign masses and 467 images of 144 malignant masses for training data. Deep learning model was constructed using CNN architecture GoogLeNet and analyzed test data: 48 benign masses, 72 malignant masses. Three radiologists interpreted these test data. Sensitivity, specificity, accuracy, and area under the receiver operating characteristic curve (AUC) were calculated.

resultsThe CNN model and radiologists had a sensitivity of 0.958 and 0.583-0.917, specificity of 0.925 and 0.604-0.771, and accuracy of 0.925 and 0.658-0.792, respectively. The CNN model had equal or better diagnostic performance compared to radiologists (AUC = 0.913 and 0.728-0.845, p = 0.01-0.14).

conclusionDeep learning with CNN shows high diagnostic performance to discriminate between benign and malignant breast masses on ultrasound.

Indexed as

Deep LearningAdultAgedAged, 80 and overBreastBreast NeoplasmsDatabases, FactualDiagnosis, DifferentialFemaleHumansImage Interpretation, Computer-AssistedMiddle AgedNeural Networks, ComputerReproducibility of ResultsRetrospective StudiesROC CurveArtificial intelligenceBreast imagingConvolutional neural networkDeep learningUltrasound

Identifiers

PMID30888570
OpenAlexW2939142770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.