Evidence map›Paper›PMID 30888550›Full record

ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2019

Pathogenic mechanisms and current epidemiological status of HEV infection in asymptomatic blood donors and patients with chronic diseases.

L Albano, Maria Vasco, G Benincasa, L Sommese, R Alfano, C Napoli

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Synergistic Effects of a Novel Combination of Natural Compounds Prevent HInternational journal of molecular sciences · 2025
    Article
  2. Undiagnosed liver diseases.Translational gastroenterology and hepatology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

L AlbanoDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Maria VascoU.O.C. Division of Clinical Immunology, Immunohematology, Transfusion Medicine and Transplant Immunology, University of Campania "Luigi Vanvitelli", Naples, Italy. maria.vasco@policliniconapoli.it.ORCID http://orcid.org/0000-0003-3740-7907
G BenincasaUniversity Department of Advanced Medical and Surgical Sciences, Clinical Department of Internal Medicine and Specialistic Units (DAI), University of Campania "Luigi Vanvitelli", Naples, Italy.
L SommeseDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
R AlfanoUniversity Department of Advanced Medical and Surgical Sciences, Clinical Department of Internal Medicine and Specialistic Units (DAI), University of Campania "Luigi Vanvitelli", Naples, Italy.
C NapoliUniversity Department of Advanced Medical and Surgical Sciences, Clinical Department of Internal Medicine and Specialistic Units (DAI), University of Campania "Luigi Vanvitelli", Naples, Italy.
University of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the seroprevalence of anti-hepatitis E virus immunoglobulins (HEV) has increased in European countries with significant variability among the different geographical areas. HEV infection is spread in a wide range of animal species of which domestic pigs and wild boar represent the main reservoirs of genotype 3 and 4 (the genotypes present also in Europe). European citizens are incidental hosts, mainly infected by direct contact or consumption of foods derived from undercooked or insufficient hygiene handling infected pork products or wild boar meat. Epidemiologically, the HEV incidence is low in humans but serological data show a high proportion of subclinical infection caused by genotypes 3 or 4. In the general population, asymptomatic infection represents a high potential risk in particular subjects such as blood component recipients or occupationally exposed workers. This review offers a landscape of the current epidemiological status of HEV infection (genotypes 1, 2, 3, 4, 7) both in European asymptomatic subjects, patients with chronic diseases, and domestic pig impact on humans. We also underline advantages/disadvantages of high sensitivity and specificity tests using for detecting viral RNA or anti-HEV antibodies.

Indexed as

Blood DonorsAnimalsAsymptomatic InfectionsChronic DiseaseEuropeGenotypeHepatitis AntibodiesHepatitis EHepatitis E virusHumansRed MeatRNA, ViralSeroepidemiologic StudiesSus scrofaSwineHepatitis AntibodiesRNA, ViralELISAEpidemiologyEuropean populationsHEVPatientsqRT-PCR

Identifiers

PMID30888550
OpenAlexW2927273306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.