SynthesisActa diabetologica2019
Spousal diabetes status as a risk factor for incident type 2 diabetes: a prospective cohort study and meta-analysis.
Synthesis in Acta diabetologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- Article
- Beyond Genes: Mechanistic and Epidemiological Insights into Paternal Environmental Influence on Offspring Health.Current environmental health reports · 2025Review
- The role of family health climate in physical activity and sedentary behaviour in primary care patients with diabetes - a cross-sectional study.BMC primary care · 2025Article
- Partnership and marriage and risk of type 2 diabetes: a narrative review.Diabetologia · 2025Review
- Family history of type 2 diabetes and the risk of type 2 diabetes among young and middle-aged adults.Chronic diseases and translational medicine · 2025Article
- The association between an individual's development of non-communicable diseases and their spouse's development of the same disease: the Longitudinal Survey of Middle-aged and Elderly Persons.Environmental health and preventive medicine · 2025Article
- One Question, Many Results—Why Epidemiological Studies Yield Heterogeneous Findings. Part 34 of a Series on Evaluation of Scientific Publications.Deutsches Arzteblatt international · 2024Review
- Paternal metformin use and risk of congenital malformations in offspring in Norway and Taiwan: population based, cross national cohort study.BMJ (Clinical research ed.) · 2024Article
- Relationship between Marriage and Prediabetes among Healthcare Workers: Mediating Effect of Triglycerides.Medicina (Kaunas, Lithuania) · 2024Observational
- Patterns of Gestational Hypertension or Preeclampsia Across 2 Pregnancies in Relationship to Chronic Hypertension Development: A Retrospective Cohort Study.Journal of the American Heart Association · 2024Article
- Paternal Use of Metformin During the Sperm Development Period Preceding Conception and Risk for Major Congenital Malformations in Newborns.Annals of internal medicine · 2024Article
- Aggregation of type-2 diabetes, prediabetes, and metabolic syndrome in German couples.Scientific reports · 2024Article
- Spousal Cognitive Status and Risk for Declining Cognitive Function and Dementia: The Atherosclerosis Risk in Communities Study.Journal of aging and health · 2023Article
- Association of Spousal Diabetes Status and Ideal Cardiovascular Health Metrics With Risk of Incident Diabetes Among Chinese Adults.JAMA network open · 2023Article
- Associations between partner's diet undermining and poor diet in mixed-weight, older gay married couples: a dyadic mediation model.Psychology & health · 2021Article
- Spousal concordance in pathophysiological markers and risk factors for type 2 diabetes: a cross-sectional analysis of The Maastricht Study.BMJ open diabetes research & care · 2021Article
- The shared risk of diabetes between dog and cat owners and their pets: register based cohort study.BMJ (Clinical research ed.) · 2020Article
- Employment transitions for spouses of stroke survivors: evidence from Swedish national registries.BMC public health · 2020Article
- Article
- Spousal metabolic risk factors and incident hypertension: A longitudinal cohort study in Iran.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
aimsIt is unclear if the presence of type-2 diabetes in one spouse is associated with the development of diabetes in the other spouse. We studied the concordance of diabetes among black and white participants in the Atherosclerosis Risk in Communities (ARIC) study and summarized existing studies in a meta-analysis.
methodsWe conducted a prospective cohort analysis of ARIC data from 8077 married men and women (mean age 54 years) without diabetes at baseline (1987-1989). Complementary log-log models that accounted for interval censoring was used to model the hazard ratio (HR) for the association of spousal diabetes status with the incidence of diabetes. For the meta-analysis, we searched MEDLINE and EMBASE for observational studies published through December 2018 that evaluated spousal concordance for diabetes.
resultsDuring a median follow-up of 22 years, 2512 incident cases of diabetes were recorded. In models with adjustment for general adiposity, spousal cardiometabolic factors and other diabetes risk factors, adults who had a spouse with diabetes had elevated risk for incident diabetes compared to those without a spouse diagnosed with diabetes (HR 1.20, 95% confidence interval 1.02-1.41). This association did not differ by sex or race. Summarized estimates from the 17 studies (489,798 participants from 9 countries) included in the meta-analysis showed a positive association between spousal diabetes status and the development of diabetes (Pooled odds ratio 1.88, 95% CI 1.52-2.33).
conclusionsResults from this large prospective biracial cohort and meta-analysis provides evidence that spouses of persons with diabetes are a high-risk group for diabetes.
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