ArticleEuropean radiology2019
Objective and subjective comparison of virtual monoenergetic vs. polychromatic images in patients with pancreatic ductal adenocarcinoma.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 53 citations in OpenAlex.
- Quantitative and qualitative evaluation of pancreatic cancer on photon-counting detector CT and dual-energy CT using standard reference images.Abdominal radiology (New York) · 2026Article
- Dual-layer spectral detector computed tomography for improving the demonstration of the communication between intraductal papillary mucinous neoplasms and pancreatic duct.Quantitative imaging in medicine and surgery · 2025Article
- Objective assessment of diagnostic image quality in CT scans: what radiologists and researchers need to know.Insights into imaging · 2025Review
- Spectral attenuation curves of photon-counting detector CT scans for the differentiation between mucinous and non-mucinous cyst fluids of pancreatic lesions - a proof-of-concept study.BMC medical imaging · 2025Article
- Optimal virtual monoenergy for the detection of pancreatic adenocarcinoma during the pancreatic parenchymal phase on photon counting CT.Abdominal radiology (New York) · 2025Article
- Optimizing Imaging Parameters for Assessment of Hepatocellular Carcinoma Using Photon-Counting Detector Computed Tomography-Impact of Reconstruction Kernel and Slice Thickness.Tomography (Ann Arbor, Mich.) · 2025Article
- Photon-counting detector computed tomography: iodine density versus virtual monoenergetic imaging of pancreatic ductal adenocarcinoma.Abdominal radiology (New York) · 2025Article
- The Usefulness of Low-Kiloelectron Volt Virtual Monochromatic Contrast-Enhanced Computed Tomography with Deep Learning Image Reconstruction Technique in Improving the Delineation of Pancreatic Ductal Adenocarcinoma.Journal of imaging informatics in medicine · 2025Article
- An update on pancreatic cancer imaging, staging, and use of the PACT-UK radiology template pre- and post-neoadjuvant treatment.The British journal of radiology · 2025Review
- Diagnostic Value of Contrast-Enhanced Dual-Energy Computed Tomography in the Pancreatic Parenchymal and Delayed Phases for Pancreatic Cancer.Tomography (Ann Arbor, Mich.) · 2024Article
- Investigation of abdominal artery delineation by photon-counting detector CT.La Radiologia medica · 2024Article
- Imaging of pancreatic ductal adenocarcinoma - An update for all stages of patient management.European journal of radiology open · 2024Article
- Preliminary Experience with Virtual Monoenergetic Imaging and Iodine Mapping in the Primary Staging of Endometrial Cancer.Cancers · 2024Article
- Optimal conspicuity of pancreatic ductal adenocarcinoma in virtual monochromatic imaging reconstructions on a photon-counting detector CT: comparison to conventional MDCT.Abdominal radiology (New York) · 2024Article
- [Current CT developments in imaging of pancreatic diseases].Radiologie (Heidelberg, Germany) · 2023Review
- Thoracic Diseases: Technique and Applications of Dual-Energy CT.Diagnostics (Basel, Switzerland) · 2023Review
- Article
- Evaluation of optimal monoenergetic images acquired by dual-energy CT in the diagnosis of T staging of thoracic esophageal cancer.Insights into imaging · 2023Article
- Correlation between Pancreatic Duct Variation and Related Diseases: An Effective Method Observing the Dual-Energy CT with Low-keV Monoenergetic Images.Diagnostics (Basel, Switzerland) · 2023Article
- Dual-energy CT with virtual monoenergetic images and iodine maps improves tumor conspicuity in patients with pancreatic ductal adenocarcinoma.Insights into imaging · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesThe aim of this study was to assess the objective and subjective image characteristics of monoenergetic images (MEI[+]), using a noise-optimized algorithm at different kiloelectron volts (keV) compared to polyenergetic images (PEI), in patients with pancreatic ductal adenocarcinoma (PDAC).
methodsThis retrospective, institutional review board-approved study included 45 patients (18 male, 27 female; mean age 66 years; range, 42-96 years) with PDAC who had undergone a dual-energy CT (DECT) of the abdomen for staging. One standard polyenergetic image (PEI) and five MEI(+) images in 10-keV intervals, ranging from 40 to 80 keV, were reconstructed. Line-density profile analysis, as well as the contrast-to-noise ratio (CNR) of the tumor, the signal-to-noise ratio (SNR) of the regular pancreas parenchyma and the tumor, and the CNR of the three main peripancreatic vessels, was calculated. For subjective quality assessment, two readers independently assessed the images using a 5-point Likert scale. Reader reliability was evaluated using an intraclass correlation coefficient.
resultsLine-density profile analysis revealed the largest gradient in attenuation between PDAC and regular tissue in MEI(+) at 40 keV. Low-keV MEI(+)reconstructions at 40 and 50 keV increased CNR and SNR compared to PEI (40 keV: CNR 46.8 vs. 7.5; SNR
conclusionMEI(+) reconstructions at 40 keV and 50 keV provide better objective and subjective image quality compared to conventional PEI of DECT in patients with PDAC. KEY POINTS: • Low-keV MEI(+) reconstructions at 40 and 50 keV increase tumor-to-pancreas contrast compared to PEI. • Low-keV MEI(+) reconstructions improve objective and subjective image quality parameters compared to PEI. • Dual-energy post-processing might be a valuable tool in the diagnostic workup of patients with PDAC.
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Registered trials
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