ArticleEuropean radiology2019
Image quality and diagnostic value of ultra low-voltage, ultra low-contrast coronary CT angiography.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Evaluation of image quality on low contrast media with deep learning image reconstruction algorithm in prospective ECG-triggering coronary CT angiography.The international journal of cardiovascular imaging · 2024Trial
- Diagnostic performance of coronary computed tomography (CT) angiography without electrocardiographic (ECG)-gating: comparison with invasive coronary angiography.Quantitative imaging in medicine and surgery · 2026Article
- The application value of deep learning-based reconstruction combined with segmented contrast injection in "one-stop" cardio-cerebrovascular computed tomography angiography.Quantitative imaging in medicine and surgery · 2025Article
- The research advancements on the advantages and limitations of coronary computed tomography angiography at low tube voltage: a literature review.Quantitative imaging in medicine and surgery · 2025Review
- Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium doses.European journal of radiology open · 2025Article
- Impact of the ADMIRE reconstruction algorithm combined with the Sa36 kernel on quantitative measurement of coronary artery calcification in AI: a single-arm prospective study.Polish journal of radiology · 2025Article
- Comparing image quality of coronary CT angiography with and without ECG-gating in wide-detector CT.Frontiers in cardiovascular medicine · 2025Article
- Effects of low-tube voltage coronary CT angiography on plaque and pericoronary fat assessment: intraindividual comparison.European radiology · 2024Article
- Influencing factors and improvement methods of coronary artery plaque evaluation in CT.Frontiers in cardiovascular medicine · 2024Review
- Effects of combining multiple dose reduction techniques on coronary computed tomography angiography.World journal of radiology · 2023Article
- Intraindividual evaluation of effects of image filter function on image quality in coronary computed tomography angiography.Frontiers in cardiovascular medicine · 2022Article
- Progress of CT aortic angiography combined with coronary artery in the evaluation of acute aortic syndrome.Frontiers in cardiovascular medicine · 2022Review
- The ultrafast, high-pitch turbo FLASH mode of third-generation dual-source CT: Effect of different pitch and corresponding SFOV on image quality in a phantom study.Journal of applied clinical medical physics · 2021Article
- Low dose contrast media in step-and-shoot coronary angiography with third-generation dual-source computed tomography: feasibility of using 30 mL of contrast media in patients with body surface area <1.7 mQuantitative imaging in medicine and surgery · 2021Article
- Cardiac CT perfusion and FFRCardiovascular diagnosis and therapy · 2020Review
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the image quality (IQ) and diagnostic value of 70 kVp turbo high-pitch coronary CT angiography (THP-CCTA) using automated tube voltage selection (ATVS) and 30 mL of low-concentration contrast agent.
methodsPatients who underwent 70 kVp THP-CCTA using ATVS with 30 mL of contrast agent (group A) were prospectively enrolled, and those who underwent conventional CCTA (100/120 kVp, prospective sequential mode with 65-75 mL of contrast agent) (group B) were retrospectively selected for study. IQ was assessed subjectively on a 5-point scale, and diagnostic value was assessed based on invasive coronary angiography as the gold standard. Heart rate (HR), HR fluctuation (HRF), body mass index (BMI), effective radiation dose (ED), and iodine uptake (IU) were recorded.
resultsA total of 796 patients (398/398 in groups A/B) were included. Between-group differences in age, gender, BMI, HR, HRF, and IQ values were not significant. The ED/IU values were 0.3 ± 0.1 mSv/9.0 ± 0.0 g and 5.8 ± 1.8 mSv/22.9 ± 1.0 g in groups A and B, respectively (p < 0.01). The sensitivity, specificity, positive and negative predictive values, and accuracy of THP-CCTA for the diagnosis of ≥ 50% stenosis were 94.8%, 97.5%, 92.0%, 98.4%, and 96.9% respectively. The mean HR and coronary calcium score were independent predictors of diagnostic image quality, and the best cutoff values were 71.5 bpm and 444.1 respectively.
conclusionThis third-generation dual-source CT imaging modality, a 70-kVp THP-CCTA system using ATVS with 30 mL of low-concentration contrast agent, produces high-quality images with high diagnostic accuracy for significant stenosis, with ultra low ED and IU. This technique was most promising in individuals with an HR < 71.5 bpm and coronary calcium score < 444.1. KEY POINTS: • Turbo high-pitch CCTA using 70 kVp via automated tube voltage selection and 30 mL of low-concentration contrast agent is feasible. • This protocol provides high diagnostic accuracy for significant coronary stenosis and reduces radiation doses and iodine uptake significantly. • This protocol was most promising in individuals with an HR < 71.5 bpm and coronary calcium score < 444.1.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.