Evidence map›Paper›PMID 30888440›Full record

ReviewIntensive care medicine2019

Obesity in the critically ill: a narrative review.

Miet Schetz, Audrey De Jong, Adam M Deane, Wilfried Druml, Pleun Hemelaar, Paolo Pelosi, Peter Pickkers, Annika Reintam-Blaser, Jason Roberts, Yasser Sakr and 1 more

Registry-linked trialOpen access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Intensive care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07032207 (The Correlation of Gastric Residual Volume Detected by Preoperative Gastric Ultrasonography With Body Mass Index and Aspiration Risk in Patients Undergoing Laparoscopic Bariatric Surgery), which is not on this map. Cited by 269 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
269citing papers in PubMed, 6 pooled it
32.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07032207 completednot on this mapstarted 2024, after this paper: background citation

The Correlation of Gastric Residual Volume Detected by Preoperative Gastric Ultrasonography With Body Mass Index and Aspiration Risk in Patients Undergoing Laparoscopic Bariatric Surgery

TypeobservationalSponsorFatih Sultan Mehmet Training and Research HospitalRan2024 to 2026Enrolled60ConditionsObesity, Gastric Ultrasound, Gastric Residual Volume, Body Mass Index (BMI)
3 · Its place in the literature

Who cites it

269 citing papers in PubMed, 6 syntheses or guidelines pooled it, 538 citations in OpenAlex.

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  11. Body mass index and hospital mortality in mechanically ventilated patients with acute hypoxaemic respiratory failure: A retrospective cohort study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026
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209 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 9 countries.

Miet SchetzDivision of Cellular and Molecular Medicine, Clinical Department and Laboratory of Intensive Care Medicine, KU Leuven University, Herestraat 49, 3000, Leuven, Belgium. marie.schetz@uzleuven.be.ORCID 0000-0001-5776-4827
Audrey De JongAnesthesia and Critical Care Department (DAR-B), Saint Eloi, University of Montpellier, Research Unit: PhyMedExp, INSERM U-1046, CNRS, 34295, Montpellier Cedex 5, France.
Adam M DeaneDepartment of Medicine and Radiology, Melbourne Medical School, Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC, Australia.
Wilfried DrumlKlinik für Innere Medizin III, Abteilung für Nephrologie, Allgemeines Krankenhaus Wien, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Pleun HemelaarDepartment of Intensive Care Medicine (710), Radboud University Medical Centre, Geert Grooteplein Zuid 10, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Paolo PelosiDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.
Peter PickkersDepartment of Intensive Care Medicine (710), Radboud University Medical Centre, Geert Grooteplein Zuid 10, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Annika Reintam-BlaserDepartment of Intensive Care Medicine, Lucerne Cantonal Hospital, Lucerne, Switzerland.
Jason RobertsUniversity of Queensland Centre for Clinical Research, Faculty of Medicine, University of Queensland, Herston, Australia.
Yasser SakrDepartment of Anesthesiology and Intensive Care, Uniklinikum Jena, Jena, Germany.
Samir JaberAnesthesia and Critical Care Department (DAR-B), Saint Eloi, University of Montpellier, Research Unit: PhyMedExp, INSERM U-1046, CNRS, 34295, Montpellier Cedex 5, France.
Centre National de la Recherche Scientifique · FRRadboud University Nijmegen · NLBarmherzige Schwestern Krankenhaus Wien · ATJena University Hospital · DEKU Leuven · BEOspedale Policlinico San Martino · ITThe Royal Melbourne Hospital · AUThe University of Queensland · AUUniversity of Lucerne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization defines overweight and obesity as the condition where excess or abnormal fat accumulation increases risks to health. The prevalence of obesity is increasing worldwide and is around 20% in ICU patients. Adipose tissue is highly metabolically active, and especially visceral adipose tissue has a deleterious adipocyte secretory profile resulting in insulin resistance and a chronic low-grade inflammatory and procoagulant state. Obesity is strongly linked with chronic diseases such as type 2 diabetes, hypertension, cardiovascular diseases, dyslipidemia, non-alcoholic fatty liver disease, chronic kidney disease, obstructive sleep apnea and hypoventilation syndrome, mood disorders and physical disabilities. In hospitalized and ICU patients and in patients with chronic illnesses, a J-shaped relationship between BMI and mortality has been demonstrated, with overweight and moderate obesity being protective compared with a normal BMI or more severe obesity (the still debated and incompletely understood "obesity paradox"). Despite this protective effect regarding mortality, in the setting of critical illness morbidity is adversely affected with increased risk of respiratory and cardiovascular complications, requiring adapted management. Obesity is associated with increased risk of AKI and infection, may require adapted drug dosing and nutrition and is associated with diagnostic and logistic challenges. In addition, negative attitudes toward obese patients (the social stigma of obesity) affect both health care workers and patients.

Indexed as

Body Mass IndexCritical IllnessGlobal HealthHumansObesityPrevalenceRespiratory Distress SyndromeWorld Health OrganizationComplicationsCritically illMortality paradoxObesity

Identifiers

PMID30888440
OpenAlexW2924743030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.