Evidence map›Paper›PMID 30888238›Full record

ArticleXenobiotica; the fate of foreign compounds in biological systems2020

Metabolism of cyclic phenones in rainbow trout

Jose Serrano, Mark A Tapper, Richard C Kolanczyk, Barbara R Sheedy, Tylor Lahren, Dean E Hammermeister, Jeffrey S Denny, Michael W Hornung, Alena Kubátová, Patricia A Kosian and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Xenobiotica; the fate of foreign compounds in biological systems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Xenobiotica; the fate of foreign compounds in biological systems · 2021
    Article
  2. Xenobiotica; the fate of foreign compounds in biological systems · 2020
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jose SerranoMid-Continent Ecology Division, USEPA, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Duluth, MN, USA.
Mark A TapperMid-Continent Ecology Division, USEPA, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Duluth, MN, USA.
Richard C KolanczykMid-Continent Ecology Division, USEPA, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Duluth, MN, USA.
Barbara R SheedyMid-Continent Ecology Division, USEPA, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Duluth, MN, USA.
Tylor LahrenMid-Continent Ecology Division, USEPA, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Duluth, MN, USA.
Dean E HammermeisterMid-Continent Ecology Division, USEPA, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Duluth, MN, USA.
Jeffrey S DennyMid-Continent Ecology Division, USEPA, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Duluth, MN, USA.
Michael W HornungMid-Continent Ecology Division, USEPA, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Duluth, MN, USA.
Alena KubátováDepartment of Chemistry, University of North Dakota, Grand Forks, ND, USA.ORCID http://orcid.org/0000-0002-2318-5883
Patricia A KosianMid-Continent Ecology Division, USEPA, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Duluth, MN, USA.
Jessica VoelkerMid-Continent Ecology Division, Student Services Contractor, Duluth, MN, USA.
Patricia K SchmiederMid-Continent Ecology Division, USEPA, Office of Research and Development, National Health and Environmental Effects Research Laboratory, Duluth, MN, USA.
Environmental Protection Agency · USUniversity of North Dakota · US

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

1. Cyclic phenones are chemicals of interest to the USEPA due to their potential for endocrine disruption to aquatic and terrestrial species.2. Prior to this report, there was very limited information addressing metabolism of cyclic phenones by fish species and the potential for estrogen receptor (ER) binding and vitellogenin (Vtg) gene activation by their metabolites.3. The main objectives of the current research were to characterize rainbow trout (rt) liver slice-mediated

Indexed as

AnimalsBenzophenonesChromatography, LiquidEndocrine DisruptorsEstrogensOncorhynchus mykissTandem Mass SpectrometryVitellogeninsBenzophenonesEndocrine DisruptorsEstrogensVitellogeninsendocrine disruptionestrogen receptorFish metabolismin vitroprecision-cut liver slicesvitellogenin gene expression

Identifiers

PMID30888238
PMCPMC9726639
OpenAlexW2924014425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.