ArticleACS applied materials & interfaces2019
Extended Nitric Oxide-Releasing Polyurethanes via S-Nitrosothiol-Modified Mesoporous Silica Nanoparticles.
Article in ACS applied materials & interfaces, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Blue Light-Mediated Nitric Oxide-Releasing Formulation for the Multimodal Treatment of Acne Vulgaris.Advanced healthcare materials · 2026Article
- Treatment of periodontal biofilms via nitric oxide-augmented phototherapy.Journal of oral microbiology · 2026Article
- Investigation of the susceptibility of clinical infection loads to nitric oxide antibacterial treatment.Nitric oxide : biology and chemistry · 2025Article
- Nitric Oxide in Biomaterial-Based Therapies for Coronary Heart Disease: Mechanistic Insights, Current Advances, and Translational Prospects.Biomaterials research · 2025Review
- Nitric Oxide Releasing Nanomaterials for Cardiovascular Applications.JACC. Basic to translational science · 2024Review
- Sterilization Effects on Nitric Oxide-Releasing Glucose Sensors.Sensors and actuators. B, Chemical · 2024Article
- A CIA strategy with eminent drug-loading capacities for tumor ferroptosis-gas synergistic therapy.Theranostics · 2024Article
- Mechanisms of Foreign Body Response Mitigation by Nitric Oxide Release.International journal of molecular sciences · 2022Article
- Long-Term Storage Stability and Nitric Oxide Release Behavior of (ACS applied materials & interfaces · 2022Article
- Nitric Oxide Release and Antibacterial Efficacy Analyses ofACS applied bio materials · 2022Article
- Biological Effects, Applications and Design Strategies of Medical Polyurethanes Modified by Nanomaterials.International journal of nanomedicine · 2022Review
- Article
- Nanomaterial Nitric Oxide Delivery in Traumatic Orthopedic Regenerative Medicine.Frontiers in bioengineering and biotechnology · 2020Review
- Long-Term Accurate Continuous Glucose Biosensors via Extended Nitric Oxide Release.ACS sensors · 2019Article
- Nitric Oxide-Releasing Polymeric Materials for Antimicrobial Applications: A Review.Antioxidants (Basel, Switzerland) · 2019Review
- Crystal-facet-dependent denitrosylation: modulation of NO release fromChemical science · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
S-Nitrosothiol (RSNO)-modified mesoporous silica nanoparticles (MSNs) were doped into polyurethane (PU) to achieve extended NO-releasing coatings. Parameters influencing the synthesis of RSNO-functionalized nitric oxide (NO)-releasing MSNs were evaluated to elucidate the impact of pore structure on NO release characteristics. The porous particles were characterized as having larger NO payloads and longer NO release durations than those of nonporous particles, a feature attributed to the recombination of the NO radical in confined intraporous microenvironments. NO release kinetics, particle leaching, and thermal stability of the RSNO-modified MSNs dispersed in PU were evaluated as a function of PU structure to determine the feasibility of preparing a range of NO-releasing polymers for biomedical device-coating applications. The NO release kinetics from the PUs proved to be highly extended (>30 d) and consistent over a range of PU properties. Furthermore, RSNO-modified MSN leaching was not observed from the PUs. The NO release payloads were also maintained for 4 days for polymers stored at 0 °C.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.