Evidence map›Paper›PMID 30888083›Full record

ReviewCancer science2019

In commemoration of the 2018 Mataro Nagayo Prize: A road to early diagnosis and monitoring of asbestos-related mesothelioma.

Okio Hino, Masaaki Abe, Bo Han, Yan Yan

Abstract readReview
In one paragraph

Review in Cancer science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Okio HinoDepartment of Pathology and Oncology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Masaaki AbeDepartment of Pathology and Oncology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Bo HanDepartment of Molecular Pathogenesis, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Yan YanDepartment of Molecular Pathogenesis, Graduate School of Medicine, Juntendo University, Tokyo, Japan.ORCID https://orcid.org/0000-0002-6272-0439

Funding

Foundation of Strategic Research Projects in Private Universities of the NEXT (Ministry of Education, Culture, Sports, Science and Technology of Japan) S1311011Foundation of Strategic Research Projects in Private Universities of the NEXT (Ministry of Education, Culture, Sports, Science and Technology of Japan) S1511008LInstitute for Environmental and Gender-Specific Medicine of Juntendo University Urayasu HospitalMinistry of Education, Culture, Sports, Science and Technology of Japan 221S0001Shizuoka Medical Research Center for Disaster of Juntendo University Shizuoka Hospital
6 · The paper itself

Abstract

Primarily caused by exposure to asbestos, mesothelioma is a typical occupational disease. The latency of mesothelioma is as long as 20-40 years, and the cancer initially progresses mainly along the surfaces of pleura or peritoneum without forming masses. As symptoms do not develop until late stages, it has been challenging to diagnose this disease in its early stages and to carry out complete surgical removal. In responding to Japan's asbestos crisis in the mid-2000s, we have developed and improved ERC/MSLN-based serum and radiological markers and pioneered the use of an N-ERC ELISA kit for screening populations at risk for asbestos exposure. In the present article, we review our research toward early diagnosis of asbestos-related mesothelioma before symptoms develop and share our clinical experience of screening, diagnosing and monitoring of this disease. This paper is dedicated to the author (Dr Okio Hino) to commemorate the honor bestowed upon him as the recipient of the Mataro Nagayo Prize in 2018.

Indexed as

AnimalsAsbestosAwards and PrizesBiomarkers, TumorDisease ManagementEarly Detection of CancerHumansJapanLung NeoplasmsMesothelinMesotheliomaMesothelioma, MalignantOccupational DiseasesOncogene ProteinsAsbestosBiomarkers, TumorErc protein, humanMesothelinMSLN protein, humanOncogene Proteinsasbestosearly diagnosisERCmesotheliomaoccupational disease

Identifiers

PMID30888083
PMCPMC6500980

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.