ArticleThe American journal of tropical medicine and hygiene2019
Clinical Utility of Platelet Count as a Prognostic Marker for Melioidosis.
Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The Predictive Factors Associated with In-Hospital Mortality of Melioidosis: A Cohort Study.Medicina (Kaunas, Lithuania) · 2024Article
- Seroprevalence of melioidosis and its association with blood profiles and pathogens in sheltered dogs in southern Thailand.Veterinary world · 2024Article
- The Epidemiological, Clinical, and Microbiological Features of Patients withTropical medicine and infectious disease · 2023Article
- Platelet‑related parameters as potential biomarkers for the prognosis of sepsis.Experimental and therapeutic medicine · 2023Article
- Melioidosis: Laboratory Investigations and Association with Patient Outcomes.The American journal of tropical medicine and hygiene · 2021Article
- The Cox model of predicting mortality among melioidosis patients in Northern Malaysia: A retrospective study.Medicine · 2021Article
- Platelets and Their Role in the Pathogenesis of Cardiovascular Events in Patients With Community-Acquired Pneumonia.Frontiers in immunology · 2020Review
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5 authors.
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Abstract
Thromobocytopenia predicts mortality in patients with melioidosis in Thailand. We analyzed platelet counts in two large cohorts of melioidosis patients in tropical northern Australia to assess utility in a different clinical setting. Admission platelet counts were compared between subgroups of patients with different clinical outcomes. Patients with more severe disease (indicated by bacteremia, septic shock, and death) had significantly lower platelet counts than those with less severe disease. Logistic regression analysis was carried out for potential predictors of mortality among various clinical parameters, and platelet count was shown to be an independent predictor of mortality. Furthermore, in patients critically ill with melioidosis, an increasing platelet count after admission was associated with a significantly greater chance of survival. However, given that most patients with severe disease still had platelet counts within the normal range, platelet count is not a useful biomarker for predicting the severity of melioidosis in a clinical context.
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