Evidence map›Paper›PMID 30887831›Full record

ArticleAIDS care2019

Adverse childhood experiences, mental health, substance use, and HIV-related outcomes among persons with HIV.

Kelly C Young-Wolff, Varada Sarovar, Stacy A Sterling, Amy Leibowitz, Brigid McCaw, Charles B Hare, Michael J Silverberg, Derek D Satre

Abstract read
In one paragraph

Article in AIDS care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  11. Mediating roles of social support in lives of men who have sex with men living with HIV.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
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  20. Childhood trauma, substance use and depressive symptoms in people with HIV during COVID-19.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kelly C Young-Wolffa Division of Research, Kaiser Permanente , Oakland , CA , USA.
Varada Sarovara Division of Research, Kaiser Permanente , Oakland , CA , USA.
Stacy A Sterlinga Division of Research, Kaiser Permanente , Oakland , CA , USA.
Amy Leibowitza Division of Research, Kaiser Permanente , Oakland , CA , USA.
Brigid McCawc Family Violence Prevention Program, Kaiser Permanente , Oakland , CA , USA.
Charles B Hared Department of Adult and Family Medicine, Kaiser Permanente San Francisco Medical Center , San Francisco , CA , USA.
Michael J Silverberga Division of Research, Kaiser Permanente , Oakland , CA , USA.
Derek D Satrea Division of Research, Kaiser Permanente , Oakland , CA , USA.

Funding

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients, U01AA021997 Admin SupplementU01AA021997 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SATRE, DEREK D, SILVERBERG, MICHAEL J · 2012 to 2017
$2.9M
Mentoring alcohol use intervention research in HIV health care settingsK24AA025703 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Derek D Satre · 2018 to 2026
$1.8M
Identifying Risk Factors for Prenatal Substance and Polysubstance UseK01DA043604 · NIDA · KAISER FOUNDATION RESEARCH INSTITUTE · PI YOUNG-WOLFF, KELLY CORINNE · 2017 to 2021
$907k
NIAAA NIH HHS K24 AA025703NIAAA NIH HHS U01 AA021997NIDA NIH HHS K01 DA043604
6 · The paper itself

Abstract

While persons with HIV (PWH) have benefited from significant advances in treatment and resulting longevity, mental health problems remain elevated in this population. Adverse childhood experiences (ACEs) are common among PWH and may negatively affect mental health and HIV-related outcomes. We examined the association between ACEs, depression and anxiety symptoms, substance use, antiretroviral therapy (ART) adherence, and HIV-clinical indicators in a sample of 584 PWH at risk for unhealthy alcohol use enrolled in a primary care-based alcohol intervention study. The sample was 96.9% male, 63.0% non-Hispanic white, with an average age of 49.0 years. ACEs were highly prevalent: 82.5% reported ≥1 ACE, including 34.2% reporting 1-2 ACEs, 25.0% reporting 3-4 ACEs, and 23.3% reporting ≥5 ACEs. Adjusting for demographics, having 1-2, 3-4 or ≥5 ACEs was significantly associated with anxiety (ORs (95%CI): 3.41 (1.13-10.33), 4.36 (1.42-3.36), and 3.96 (1.28-12.19), respectively) and poorer mental health quality of life (Betas (SE): -3.21 (1.40), -6.23 (1.51), and -7.09 (1.54), respectively), but not with other outcomes. Trauma-informed interventions to reduce anxiety and improve mental health quality of life in PWH may reduce the negative health sequelae of ACEs.

Indexed as

Adverse Childhood ExperiencesMental HealthAdolescentAdultAgedAnxietyChildCross-Sectional StudiesDepressionFemaleHIV InfectionsHumansLongitudinal StudiesMaleMiddle AgedPrevalenceAdverse childhood experiencesalcoholanxietyepidemiologyHIVquality of lifetrauma

Identifiers

PMID30887831
PMCPMC6675575

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.